Microfluidic-Assisted Caenorhabditis elegans Sorting: Current Status and Future Prospects

H Yuan, W Yuan, S Duan, K Jiao, Q Zhang… - Cyborg and Bionic …, 2023 - spj.science.org
Caenorhabditis elegans (C. elegans) has been a popular model organism for several
decades since its first discovery of the huge research potential for modeling human diseases …

Microfluidic Technologies for High Throughput Screening Through Sorting and On-Chip Culture of C. elegans

D Midkiff, A San-Miguel - Molecules, 2019 - mdpi.com
The nematode Caenorhabditis elegans is a powerful model organism that has been widely
used to study molecular biology, cell development, neurobiology, and aging. Despite their …

Scalable Electrophysiology of Millimeter-Scale Animals with Electrode Devices

K Dong, WC Liu, Y Su, Y Lyu, H Huang, N Zheng… - BME …, 2023 - spj.science.org
Millimeter-scale animals such as Caenorhabditis elegans, Drosophila larvae, zebrafish, and
bees serve as powerful model organisms in the fields of neurobiology and neuroethology …

High-throughput sorting of eggs for synchronization of C. elegans in a microfluidic spiral chip

S Sofela, S Sahloul, M Rafeie, T Kwon, J Han… - Lab on a Chip, 2018 - pubs.rsc.org
In this study, we report the use of a high-throughput microfluidic spiral chip to screen out
eggs from a mixed age nematode population, which can subsequently be cultured to a …

Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

HB Atakan, R Xiang, M Cornaglia, L Mouchiroud… - Scientific reports, 2019 - nature.com
The nematode Caenorhabditis elegans is a suitable model organism in drug screening.
Traditionally worms are grown on agar plates, posing many challenges for long-term culture …

Materials and toxicological approaches to study metal and metal-oxide nanoparticles in the model organism Caenorhabditis elegans

L Gonzalez-Moragas, LL Maurer, VM Harms… - Materials …, 2017 - pubs.rsc.org
Understanding the in vivo fate and transport of nanoparticles (NPs) is challenging, but
critical. We review recent studies of metal and metal oxide NPs using the model organism …

Microfluidics-integrated spaceflight hardware for measuring muscle strength of Caenorhabditis elegans on the International Space Station

P Soni, T Anupom, L Lesanpezeshki, M Rahman… - npj …, 2022 - nature.com
Caenorhabditis elegans is a low-cost genetic model that has been flown to the International
Space Station to investigate the influence of microgravity on changes in the expression of …

Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms

L Dong, M Cornaglia, G Krishnamani, J Zhang… - PloS one, 2018 - journals.plos.org
The nematode Caenorhabditis elegans is an important model organism for biomedical
research and genetic studies relevant to human biology and disease. Such studies are often …

Microfluidic electric parallel egg-laying assay and application to in-vivo toxicity screening of microplastics using C. elegans

K Youssef, D Archonta, TJ Kubiseski, A Tandon… - Science of The Total …, 2021 - Elsevier
Environmental pollutants like microplastics are posing health concerns on aquatic animals
and the ecosystem. Microplastic toxicity studies using Caenorhabditis elegans (C. elegans) …

Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution

MC Letizia, M Cornaglia, R Trouillon… - Microsystems & …, 2018 - nature.com
The organism Caenorhabditis elegans is a performant model system for studying human
biological processes and diseases, but until now all phenome data are produced as …