Neuroscience research using small animals on a chip: from nematodes to zebrafish larvae
Implementation of microfluidic technology to study small animal models such as
Caenorhabditis elegans worms (soil-dwelling nematodes), Drosophila melanogaster (fruit …
Caenorhabditis elegans worms (soil-dwelling nematodes), Drosophila melanogaster (fruit …
Disruption of genes associated with Charcot-Marie-Tooth type 2 lead to common behavioural, cellular and molecular defects in Caenorhabditis elegans
MS Soh, X Cheng, T Vijayaraghavan, A Vernon, J Liu… - PLoS …, 2020 - journals.plos.org
Charcot-Marie-Tooth (CMT) disease is an inherited peripheral motor and sensory
neuropathy. The disease is divided into demyelinating (CMT1) and axonal (CMT2) …
neuropathy. The disease is divided into demyelinating (CMT1) and axonal (CMT2) …
Parallel-Channel Electrotaxis and Neuron Screening of Caenorhabditis elegans
In this paper, we report a novel microfluidic method to conduct a Caenorhabditis elegans
electrotaxis movement assay and neuronal imaging on up to 16 worms in parallel. C …
electrotaxis movement assay and neuronal imaging on up to 16 worms in parallel. C …
Bioenergetic Health Assessment of a Single Caenorhabditis elegans from Postembryonic Development to Aging Stages via Monitoring Changes in the Oxygen …
SH Huang, YW Lin - Sensors, 2018 - mdpi.com
Monitoring dynamic changes in oxygen consumption rates (OCR) of a living organism in real
time provide an indirect method of monitoring changes in mitochondrial function during …
time provide an indirect method of monitoring changes in mitochondrial function during …
Miniaturized sensors and actuators for biological studies on small model organisms of disease
The process of discovering a drug is extremely time consuming and expensive, requiring
extensive biochemical screening assays on cells and animal models of human diseases …
extensive biochemical screening assays on cells and animal models of human diseases …
A microfluidic device for quantitative investigation of zebrafish larvae's rheotaxis
Zebrafish is a model organism for various sensory-motor biological studies. Rheotaxis, or
the ability of zebrafish to orient and swim against the water stream, is a common behavior …
the ability of zebrafish to orient and swim against the water stream, is a common behavior …
Difference in Intestine Content of Caenorhabditis elegans When Fed on Non-Pathogenic or Pathogenic Bacteria
F Rezaeianaran, MAM Gijs - Micromachines, 2023 - mdpi.com
We investigated the bacterial food digestion and accumulation in wild-type adult
Caenorhabditis elegans (C. elegans) worms that have fed on either non-pathogenic RFP …
Caenorhabditis elegans (C. elegans) worms that have fed on either non-pathogenic RFP …
Electric egg-laying: a new approach for regulating C. elegans egg-laying behaviour in a microchannel using electric field
In this paper, the novel effect of electric field (EF) on adult C. elegans egg-laying in a
microchannel is discovered and correlated with neural and muscular activities. The …
microchannel is discovered and correlated with neural and muscular activities. The …
A design of experiment approach for efficient multi-parametric drug testing using a Caenorhabditis elegans model
MC Letizia, M Cornaglia, G Tranchida… - Integrative …, 2018 - academic.oup.com
When studying the drug effectiveness towards a target model, one should distinguish the
effects of the drug itself and of all the other factors that could influence the screening …
effects of the drug itself and of all the other factors that could influence the screening …
Microfluidic devices for imaging and manipulation of C. elegans
AS Clark, J Huayta, KS Arulalan… - Micro and Nano Systems …, 2021 - Elsevier
The nematode Caenorhabditis elegans is a model organism widely used to study
development, neuroscience, disease modeling, and aging. Due to their small size …
development, neuroscience, disease modeling, and aging. Due to their small size …