As an obligate intracellular pathogen, Chlamydia trachomatis assumes various strategies to
inhibit host cells apoptosis, thereby providing a suitable intracellular environment to ensure …

Persistent infection of Chlamydia trachomatis is thought to be responsible for the debilitating
sequelae of blinding trachoma and infertility. Inhibition of host cell apoptosis is a persistent …

Stress granule (SG) formation is a host cell response to stress-induced translational
repression. SGs assemble with RNA-binding proteins and translationally silent mRNA. SGs …

Aim Chlamydia trachomatis has evolved various strategies to alleviate oxidative stress of
host cells to maintain their intracellular survival. However, the exact mechanism of anti …

Abstract Background Natural clearance of Chlamydia trachomatis in women occurs in the
interval between screening and treatment. In vitro, interferon-γ (IFN-γ)–mediated tryptophan …

Long non-coding RNAs (lncRNAs) have been demonstrated to play essential roles in many
diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of …

Chlamydia trachomatis persistent infection is the leading cause of male prostatitis and
female genital tract diseases. Inhibition of host cell apoptosis is the key to maintaining …

Considering the shortcomings in current chlamydia infection control strategies, a major
challenge in curtailing infection is the implementation of an effective vaccine. The immune …

目的: 制备沙眼衣原体(Ct) Pgp3 蛋白的兔多克隆抗体, 并检测其生物学功能. 方法:
采用原核表达系统制备Pgp3 蛋白, 通过镍柱亲和纯化Pgp3 蛋白并进行复性. 将复性的Pgp3 …

Background Chlamydia trachomatis (Ct) is one of the most common bacterial sexually
transmitted infection (STI) pathogens in the world, but the exact pathogenic mechanism still …