Abstract Corona virus disease 2019 (COVID‐19) causes symptoms from multiple organs
after infection by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They …

Acute pancreatitis (AP) is an inflammatory disease with varied severity, ranging from mild
local inflammation to severe systemic involvement resulting in substantial mortality. Early …

Oxygen delivery to cells is the basic prerequisite of life. Within the human body, an
ingenious oxygen delivery system, comprising steps of convection and diffusion from the …

Objective: We sought to identify and investigate the functional role of the major endothelial
cell (EC)-derived factors that control pericyte recruitment to EC tubes and pericyte-induced …

The transport of oxygen between blood and tissue is limited by blood's capillary transit time,
understood as the time available for diffusion exchange before blood returns to the heart. If …

The microcirculation, comprised of less than 100 μm–diameter arterioles, capillary beds, and
draining venules, performs essential homeostatic functions, including oxygen delivery and …

The normal blood lactate level is 0–2 mmol/L, and a value above 3–5 mmol/L is variably
used to define hyperlactatemia. In cardiac surgical patients, hyperlactatemia can arise from …

As an endocrine disease, type 2 diabetes mellitus (T2DM) can cause testicular damage
which induces male infertility. However, the underlying mechanism is still not clear. We …

The vascular endothelium is crucial for the maintenance of vascular homeostasis. Moreover,
in sepsis, endothelial cells can acquire new properties and actively participate in the host's …

Purpose Inotropes and vasopressors are cornerstone of therapy in septic shock, but search
for the best agent is ongoing. We aimed to determine which vasoactive drug is associated …