[HTML][HTML] Anti-inflammatory effects of resveratrol: Mechanistic insights

D de Sá Coutinho, MT Pacheco, RL Frozza… - International journal of …, 2018 - mdpi.com
Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

Long-acting HIV drugs for treatment and prevention

RM Gulick, C Flexner - Annual review of medicine, 2019 - annualreviews.org
Antiretroviral drugs have revolutionized the treatment and prevention of HIV infection;
however, adherence is critical for sustained efficacy. Current HIV treatment consists of three …

Worldwide asthma epidemiology: insights from the Global Health Data Exchange database

C Mattiuzzi, G Lippi - International forum of allergy & rhinology, 2020 - Wiley Online Library
Background Enhanced focus on primary care provision is essential for lowering the risk of
asthma exacerbation and complications, as well as for decreasing asthma‐related …

Eosinophils increase airway sensory nerve density in mice and in human asthma

MG Drake, GD Scott, ED Blum, KM Lebold… - Science translational …, 2018 - science.org
In asthma, airway nerve dysfunction leads to excessive bronchoconstriction and cough. It is
well established that eosinophils alter nerve function and that airway eosinophilia is present …

Cellular metabolism in lung health and disease

G Liu, R Summer - Annual review of physiology, 2019 - annualreviews.org
The lung is often overlooked as a metabolically active organ, yet biochemical studies have
long demonstrated that glucose utilization surpasses that of many other organs, including …

Asthma in adults

A Nanda, AN Wasan - Medical Clinics, 2020 - medical.theclinics.com
Asthma affects approximately 300 million people worldwide and approximately 7.5% of
adults in the United States. 1, 2 Among adults, asthma results in about 10.5 million physician …

[HTML][HTML] Involvement of inflammation and its resolution in disease and therapeutics

S Alfaro, V Acuña, R Ceriani, MF Cavieres… - International Journal of …, 2022 - mdpi.com
Inflammation plays a critical role in the response to and survival from injuries and/or
infections. It occurs in two phases: initiation and resolution; however, when these events do …

[HTML][HTML] Nitric oxide system and bronchial epithelium: more than a barrier

MA Bayarri, J Milara, C Estornut, J Cortijo - Frontiers in physiology, 2021 - frontiersin.org
Airway epithelium forms a physical barrier that protects the lung from the entrance of inhaled
allergens, irritants, or microorganisms. This epithelial structure is maintained by tight …

Stem cell-based Lung-on-Chips: The best of both worlds?

JC Nawroth, R Barrile, D Conegliano, S van Riet… - Advanced drug delivery …, 2019 - Elsevier
Pathologies of the respiratory system such as lung infections, chronic inflammatory lung
diseases, and lung cancer are among the leading causes of morbidity and mortality, killing …

Inhaled drug delivery for the targeted treatment of asthma

A Boboltz, S Kumar, GA Duncan - Advanced Drug Delivery Reviews, 2023 - Elsevier
Asthma is a chronic lung disease affecting millions worldwide. While classically
acknowledged to result from allergen-driven type 2 inflammatory responses leading to IgE …