ZBTB28 induces autophagy by regulation of FIP200 and Bcl-XL facilitating cervical cancer cell apoptosis
L Li, Y Gong, K Xu, W Chen, J Xia, Z Cheng, L Li… - Journal of Experimental …, 2021 - Springer
Background Among the common preventable cancers of women, cervical cancer has the
highest morbidity. It is curable if detected at an early stage. However, reliable diagnostic and …
highest morbidity. It is curable if detected at an early stage. However, reliable diagnostic and …
Function and regulation of ULK1: From physiology to pathology
Z Rong, K Zheng, J Chen, X Jin - Gene, 2022 - Elsevier
The expression of ULK1, a core protein of autophagy, is closely related to autophagic
activity. Numerous studies have shown that pathological abnormal expression of ULK1 is …
activity. Numerous studies have shown that pathological abnormal expression of ULK1 is …
An updated review on implications of autophagy and apoptosis in tumorigenesis: possible alterations in autophagy through engineered nanomaterials and their …
Most commonly recognized as a catabolic pathway, autophagy is a perplexing mechanism
through which a living cell can free itself of excess cytoplasmic components, ie, organelles …
through which a living cell can free itself of excess cytoplasmic components, ie, organelles …
Enantioselective synthesis of indole derivatives by Rh/Pd relay catalysis and their anti-inflammatory evaluation
S Li, Z Wang, H Xiao, Z Bian, JJ Wang - Chemical Communications, 2020 - pubs.rsc.org
An efficient Rh/Pd relay catalyzed intermolecular and cascade intramolecular
hydroamination for the synthesis of exclusive trans 1-indolyl dihydronaphthalenols (up to …
hydroamination for the synthesis of exclusive trans 1-indolyl dihydronaphthalenols (up to …
Design, synthesis, and biological evaluation of polo-like kinase 1/eukaryotic elongation factor 2 kinase (PLK1/EEF2K) dual inhibitors for regulating breast cancer cells …
Z Pan, Y Chen, J Liu, Q Jiang, S Yang, L Guo… - European journal of …, 2018 - Elsevier
Abstract Both PLK1 and EEF2K are serine⁄ threonine kinases that play important roles in the
proliferation and programmed cell death of various types of cancer. They are highly …
proliferation and programmed cell death of various types of cancer. They are highly …
Targeting autophagy-related epigenetic regulators for cancer drug discovery
Y Li, G Yang, C Yang, P Tang, J Chen… - Journal of Medicinal …, 2021 - ACS Publications
Existing evidence has demonstrated that epigenetic modifications (including DNA
methylation, histone modifications, and microRNAs), which are associated with the …
methylation, histone modifications, and microRNAs), which are associated with the …
FSIP1 regulates autophagy in breast cancer
C Liu, L Sun, J Yang, T Liu, Y Yang… - Proceedings of the …, 2018 - National Acad Sciences
Fibrous sheath interacting protein 1 (FSIP1) is a cancer antigen expressed in the majority of
breast cancer tissues and is associated with poor prognosis. However, the role of FSIP1 in …
breast cancer tissues and is associated with poor prognosis. However, the role of FSIP1 in …
ULK/Atg1: phasing in and out of autophagy
Autophagy–a highly regulated intracellular degradation process–is pivotal in maintaining
cellular homeostasis. Liquid–liquid phase separation (LLPS) is a fundamental mechanism …
cellular homeostasis. Liquid–liquid phase separation (LLPS) is a fundamental mechanism …
Corneal autophagy and ocular surface inflammation: a new perspective in dry eye
S Ma, Z Yu, S Feng, H Chen, H Chen, X Lu - Experimental eye research, 2019 - Elsevier
Dry eye disease (DED), a multifactorial ocular surface disorder affecting millions of
individuals worldwide, is characterized by inflammation and damage to the ocular surface. It …
individuals worldwide, is characterized by inflammation and damage to the ocular surface. It …