Staphylococcus aureus is a formidable pathogen capable of causing infections in different
sites of the body in a variety of vertebrate animals, including humans and livestock. A major …

Staphylococcus aureus, a bacterial commensal of the human nares and skin, is a frequent
cause of soft tissue and bloodstream infections. A hallmark of staphylococcal infections is …

This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …

Staphylococcus aureus (S. aureus) is a Gram positive bacterium that is carried by about one
third of the general population and is responsible for common and serious diseases. These …

This article reviews the literature regarding the structure and function of two types of
exotoxins expressed by Staphylococcus aureus, pyrogenic toxin superantigens (PTSAgs) …

The non-covalent assembly of proteins that fold separately is central to many biological
processes, and differs from the permanent macromolecular assembly of protein subunits in …

Staphylococcus aureus is a major human pathogen that produces a wide array of toxins,
thus causing various types of disease symptoms. Staphylococcal enterotoxins (SEs), a …

Human leukocyte antigens (HLA) are cell-surface proteins that present peptides to T cells.
These peptides are bound within the peptide binding cleft of HLA, and together as a …

The crystal structure of the human cyclinA-cyclin-dependent kinase2 (CDK2)-ATP complex
has been determined at 2.3 A resolution. CyclinA binds to one side of CDK2's catalytic cleft …

▪ Abstract While still incomplete, the first data concerning the biochemistry of T cell receptor–
ligand interactions in cell-free systems seem to have considerable predictive value …