Far East Scarlet-Like Fever: A Review of the Epidemiology, Symptomatology, and Role of Superantigenic Toxin: Yersinia pseudotuberculosis-Derived Mitogen A

A Amphlett - Open forum infectious diseases, 2016 - academic.oup.com
Far East scarlet-like fever (FESLF) is a severe inflammatory disease that occurs sporadically
and in outbreaks in Russia and Japan. Far East scarlet-like fever is caused by Yersinia …

[PDF][PDF] Correlation between the number of T cell receptors required for T cell activation and TCR–ligand affinity

BA Schodin, TJ Tsomides, DM Kranz - Immunity, 1996 - cell.com
The number of T cell receptors on CTL clone 2C that are required for recognition of various
peptide–MHC or superantigen–MHC ligands were measured as a function of both the ligand …

Characterization of a novel staphylococcal enterotoxin-like superantigen, a member of the group V subfamily of pyrogenic toxins

PM Orwin, DYM Leung, TJ Tripp, GA Bohach… - Biochemistry, 2002 - ACS Publications
Staphylococcus aureus is an important human pathogen, causing a variety of diseases.
Major virulence factors of this organism include staphylococcal enterotoxins (SEs) that …

[HTML][HTML] Streptococcal superantigens: biological properties and potential role in disease

T Proft, JD Fraser - 2016 - europepmc.org
Superantigens (SAgs) are a family of highly potent mitogens that share the ability to trigger
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …

[PDF][PDF] Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II

Y Li, H Li, N Dimasi, JK McCormick, R Martin, P Schuck… - Immunity, 2001 - cell.com
MHC class II molecules possess two binding sites for bacterial superantigens (SAGs): a low-
affinity site on the α chain and a high-affinity, zinc-dependent site on the β chain. Only the …

Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin

C Orlik, D Deibel, J Küblbeck, E Balta… - Cellular & Molecular …, 2020 - nature.com
The interplay between keratinocytes and immune cells, especially T cells, plays an important
role in the pathogenesis of chronic inflammatory skin diseases. During psoriasis …

Transcytosis of staphylococcal superantigen toxins

ARA Hamad, P Marrack, JW Kappler - The Journal of experimental …, 1997 - rupress.org
Staphylococcus aureus produces a set of proteins (eg, staphylococcal enterotoxin A [SEA],
SEB, toxic shock syndrome toxin 1 [TSST-1]) which act both as superantigens (SAgs) and …

Staphylococcus aureus

NA Neg - 2007 - vetlab.com
Streptococcus agalactiae Streptococcus uberis Staphylococcus aureus Enterococcus Spp. (Not
pictured) E. coli Proteus mirabil Page 1 Organism (1) Spectrum® Gram + (2) Spectrum® Gram …

The staphylococcal enterotoxin (SE) family: SEB and siblings

T Krakauer, BG Stiles - Virulence, 2013 - Taylor & Francis
Staphylococcus aureus plays an important role in numerous human cases of food
poisoning, soft tissue, and bone infections, as well as potentially lethal toxic shock. This …

Determination of the HLA-DM interaction site on HLA-DR molecules

RC Doebele, R Busch, HM Scott, A Pashine… - Immunity, 2000 - cell.com
Abstract HLA-DM removes CLIP and other loosely bound peptides from MHC class II
molecules. The crystal structures of class II molecules and of HLA-DM have not permitted …