Cancer is the second leading cause of mortality, only overcome by cardiovascular diseases,
and has caused more than 8.7 million deaths in 2015 all over the world. This figure is …

Glioblastoma (GBM) is the most common primary malignant intracranial tumor. Due to its
high morbidity, high mortality, high recurrence rate, and low cure rate, it has brought great …

Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

Ovarian cancer remains the most lethal gynecologic malignancy with late detection and
acquired chemoresistance. Advanced understanding of the pathophysiology and novel …

The co-infection of porcine reproductive respiratory syndrome virus (PRRSV) and porcine
circovirus type 2 (PCV2) is quite common in clinical settings and no effective treatment to the …

Cancer cachexia (CC) is a debilitating multifactorial syndrome, involving progressive
deterioration and functional impairment of skeletal muscles. It affects about 80% of patients …

Matrine, a major alkaloid isolated from the traditional Chinese herb Sophora flavescens, has
been used clinically to treat breast cancer in China. However, the effects of matrine on …

Four novel matrine-based alkaloids (1–4) were isolated from the seeds of Sophora
alopecuroides. Compounds 1 and 2 possess unprecedented 6/6/6/4 and 6/5/6/6 ring …

Background Cisplatin is one of the first-line drugs for urothelial bladder cancer (UBC)
treatment. However, its considerable side effects and the emergence of drug resistance are …

Panax notoginseng is a well‐known traditional Chinese medicine, and dried flower buds of
P. notoginseng (FBP) have also been used as a medicine or tea for a long time. The …