Hypertension affects a significant proportion of the adult and aging population and
represents an important risk factor for vascular cognitive impairment and late-life dementia …

Vascular cognitive impairment and dementia (VCID) is a major heterogeneous brain
disease caused by multiple factors, and it is the second most common type of dementia in …

Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

Objectives Considerable progress has been made in the treatment of Alzheimer's disease
(AD), but all available strategies focus on alleviating symptoms rather than curing, which …

Objective: Growing evidence suggests that vascular risk factors (VRF) contribute to cognitive
decline. The aim of this study was to investigate the impact of VRF on the conversion from …

Background: Many epidemiologic studies have considered the association between blood
pressure (BP) and Alzheimer disease, yet the relationship remains poorly understood …

Background This study examined whether depression was a risk factor for onset of dementia
including Alzheimer's disease (AD), vascular dementia (VD) and any dementia, and mild …

There is wide recognition of a complex association between midlife hypertension and
cardiovascular disease and later development of Alzheimer's disease (AD) and cognitive …

Alzheimer disease (AD) is marked by profound neurodegeneration, neuroinflammation, and
cognitive decline. Pathologically, AD is characterized by the accumulation of extracellular …

Nanotechnology is an area of growing public interest. Its attractiveness stems from the
promise offered socially and economically by the recent significant advances in …