Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability
worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information …

Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …

Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

Ischemic stroke (IS) is a common neurological disorder associated with high disability rates
and mortality rates. At present, recombinant tissue plasminogen activator (r-tPA) is the only …

The pathogenesis of ischemic stroke is complex, and PI3K/Akt signaling is considered to
play a crucial role in it. The PI3K/Akt pathway regulates inflammation, oxidative stress …

The cerebral ischemic reperfusion injury may leads to morbidity and mortality in patients.
phosphatidylinositol 3-kinase (PI3K) signaling pathway has been believed to work in …

Ischemic stroke (IS) is an acute cerebrovascular disease caused by sudden arterial
occlusion, which is characterized by a high morbidity, mortality, and disability rate. It is one of …

Nuclear paraspeckle assembly transcript 1 (Neat1) located at chromosome 11 is a long non-
coding RNA that is widely expressed in mammalian cell types, and which is overexpressed …

Presently, the treatment options for ischemic stroke (IS) are limited due to the complicated
pathological process of the disease. Chuanxiong Rhizome (CR), also known as …

Intracerebral hemorrhage (ICH) can induce intensively oxidative stress, neuroinflammation,
and brain cell apoptosis. However, currently, there is no highly effective treatment available …