HIV epidemiology, prevention, treatment, and implementation strategies for public health

A Mody, AH Sohn, C Iwuji, RKJ Tan, F Venter, EH Geng - The Lancet, 2024 - thelancet.com
The global HIV response has made tremendous progress but is entering a new phase with
additional challenges. Scientific innovations have led to multiple safe, effective, and durable …

Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extra-pulmonary tuberculosis in people living with HIV

AD Kerkhoff, B Sossen, C Schutz… - European …, 2020 - Eur Respiratory Soc
Diagnosing tuberculosis (TB) in people living with HIV (PLHIV) remains challenging in part,
because of its diversity of clinical manifestations, including high rates of extra-pulmonary …

Biomarkers for tuberculosis: the case for lipoarabinomannan

M Correia-Neves, G Fröberg, L Korshun… - ERJ open …, 2019 - Eur Respiratory Soc
Tuberculosis (TB) is considered the most onerous of infectious diseases according to recent
reports from the World Health Organization. Available tests for TB diagnosis present severe …

Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms

AE Shapiro, JM Ross, M Yao, I Schiller… - Cochrane Database …, 2021 - cochranelibrary.com
Background Tuberculosis is a leading cause of infectious disease‐related death and is one
of the top 10 causes of death worldwide. The World Health Organization (WHO) …

Incidence of HIV-positive admission and inpatient mortality in Malawi (2012–2019)

RM Burke, MYR Henrion, J Mallewa, L Masamba… - Aids, 2021 - journals.lww.com
Objective: To investigate trends in population incidence of HIV-positive hospital admission
and risk of in-hospital death among adults living with HIV between 2012 and 2019 in …

Multicentre accuracy trial of FUJIFILM SILVAMP TB LAM test in people with HIV reveals lot variability

R Székely, B Sossen, M Mukoka, M Muyoyeta… - medRxiv, 2022 - medrxiv.org
Rationale There is an urgent need for rapid, non-sputum point-of-care diagnostics to detect
tuberculosis. Objectives This prospective trial in seven high tuberculosis burden countries …

Clofazimine for treatment of cryptosporidiosis in human immunodeficiency virus infected adults: an experimental medicine, randomized, double-blind, placebo …

PY Iroh Tam, SLM Arnold, LK Barrett… - Clinical Infectious …, 2021 - academic.oup.com
Background We evaluated the efficacy, pharmacokinetics (PK), and safety of clofazimine
(CFZ) in patients living with human immunodeficiency virus (HIV) with cryptosporidiosis …

Challenges and progress with diagnosing pulmonary tuberculosis in low-and middle-income countries

AD Harries, AMV Kumar - Diagnostics, 2018 - mdpi.com
Case finding and the diagnosis of tuberculosis (TB) are key activities to reach the World
Health Organization's End TB targets by 2030. This paper focuses on the diagnosis of …

Diagnostic accuracy of a novel tuberculosis point-of-care urine lipoarabinomannan assay for people living with HIV: a meta-analysis of individual in-and outpatient …

T Broger, MP Nicol, R Székely, S Bjerrum… - PLoS …, 2020 - journals.plos.org
Background Tuberculosis (TB) is the most common cause of death in people living with HIV
(PLHIV), yet TB often goes undiagnosed since many patients are not able to produce a …

Development and validation of a prognostic nomogram for HIV/AIDS patients who underwent antiretroviral therapy: data from a China population-based cohort

X Hou, D Wang, J Zuo, J Li, T Wang, C Guo, F Peng… - …, 2019 - thelancet.com
Background Accurate forecast of the death risk is crucial to the administration of people
living with HIV/AIDS (PLHIV). We aimed to establish and validate an effective prognosis …