[HTML][HTML] Antitumor activity of curcumin is mediated through the induction of apoptosis in AK-5 tumor cells

A Khar, AM Ali, BVV Pardhasaradhi, Z Begum, R Anjum - FEBS letters, 1999 - Elsevier
Curcumin, the yellow pigment of turmeric (Curcuma longa), used commonly as a spice, has
been shown to possess anticarcinogenic activity. Curcumin inhibited AK-5 tumor growth and …

Macrophages as effector cells in interleukin 12-induced T cell-dependent tumor rejection

K Tsung, JP Dolan, YL Tsung, JA Norton - Cancer research, 2002 - AACR
Abstract Interleukin (IL)-12 activates a T-cell-dependent antitumor immune response that is
able to eradicate established large tumors in a number of immunogenic tumor models. The …

[HTML][HTML] Induction of stress response renders human tumor cell lines resistant to curcumin-mediated apoptosis: role of reactive oxygen intermediates

A Khar, AM Ali, BVV Pardhasaradhi… - Cell stress & …, 2001 - ncbi.nlm.nih.gov
Curcumin, a well-known dietary pigment derived from Curcuma longa, has been shown to
be a potent anti-inflammatory, antioxidant, and anticarcinogenic compound. The present …

Increased emotional distress in daughters of breast cancer patients is associated with decreased natural cytotoxic activity, elevated levels of stress hormones and …

M Cohen, E Klein, A Kuten, G Fried… - … Journal of Cancer, 2002 - Wiley Online Library
DBCP who are aware of their increased risk of developing breast cancer may suffer from
high emotional distress. Chronic stress may interfere with NCA and low NCA is associated …

Differential expression of MHC class II molecules in highly metastatic breast cancer cells is mediated by the regulation of the CIITA transcription: Implication of CIITA in …

B Shi, A Vinyals, P Alia, C Broceño, F Chen… - The international journal …, 2006 - Elsevier
We analyzed the differential gene expression between variants of MDA-MB-435 human
breast cancer cell line that share an identical genetic background but have different …

A cross talk between cellular signalling and cellular redox state during heat-induced apoptosis in a rat histiocytoma

AS Sreedhar, BVV Pardhasaradhi, A Khar… - Free Radical Biology …, 2002 - Elsevier
Increasing evidence provides support for oxidative stress to be closely linked to apoptosis.
Reactive oxygen species (ROS) are thought to be involved in many forms of programmed …

Origin of microcells in the human sarcoma cell line HT‐1080

I Buiķis, L Harju, T Freivalds - Analytical Cellular Pathology, 1999 - content.iospress.com
The aim of this study was to investigate the development of microcells in the human sarcoma
cell line HT‐1080 after interference with thiophosphamidum. We found that damaged …

[HTML][HTML] Spontaneous remission of chronic lymphocytic leucemia in a patient with SARS-CoV2

H Bülbül, HE Nazlı, A Olgun, A Togay… - Leukemia research …, 2022 - Elsevier
Although novel therapies have improved the treatment outcome of patients, chronic
lymphocytic leukaemia (CLL) is still considered incurable. Recently, a novel coronavirus …

Induction of nitric oxide production by natural killer cells: its role in tumor cell death

MD Jyothi, A Khar - Nitric Oxide, 1999 - Elsevier
It has been recognized that natural killer (NK) cells destroy AK-5 tumor cells, largely by
cytolysis and apoptosis. The objective of this study was to elucidate the existence and the …

[HTML][HTML] Selective involvement of caspase-3 in ceramide induced apoptosis in AK-5 tumor cells

R Anjum, AM Ali, Z Begum, J Vanaja, A Khar - FEBS letters, 1998 - Elsevier
Ceramide, a product of sphingomyelin metabolism, is a novel lipid second messenger that
mediates diverse cellular functions. The present study demonstrates the activation of …