Electroacupuncture prevents the depression-like behavior by inhibiting the NF-κB/NLRP3 inflammatory pathway in hippocampus of mice subjected to chronic mild …

Q Wang, H Bi, H Huang, Y Wang, L Gong, N Qi… - …, 2022 - karger.com
Background: The precise physiological mechanisms of acupuncture in the treatment of
depression are still unknown. This study aimed to observe the effects of electroacupuncture …

The trouble with antidepressants: why the evidence overplays benefits and underplays risks—an essay by John B Warren

JB Warren - bmj, 2020 - bmj.com
The trouble with antidepressants: why the evidence overplays benefits and underplays risks—an
essay by John B Warren | The BMJ Skip to main content Intended for healthcare professionals …

What good are treatment effects without treatment? mental health and the reluctance to use talk therapy

CJ Cronin, MP Forsstrom… - Review of Economic …, 2024 - academic.oup.com
Evidence across disciplines suggests that talk therapy is more curative than antidepressants
for mild-to-moderate depression and anxiety. Yet, few patients use it. We develop a dynamic …

Trends in sales of antidepressants in Brazil from 2014 to 2020: A time trend analysis with joinpoint regression

R Hoefler, GMB Tiguman, TF Galvão… - Journal of affective …, 2023 - Elsevier
Background This study aimed to investigate the trends in antidepressants sales in Brazil.
Methods We performed a joinpoint analysis of antidepressants sales in Brazil from 2014 to …

[图书][B] Evidence-biased antidepressant prescription: Overmedicalisation, flawed research, and conflicts of interest

MP Hengartner - 2021 - Springer
Medicine is supposed to make progress, to go forward in scientific terms so that each
successive generation knows more and does better than previous generations. This hasn't …

Lifestyle psychiatry for depression and anxiety: Beyond diet and exercise

MC Piotrowski, J Lunsford, BN Gaynes - Lifestyle Medicine, 2021 - Wiley Online Library
There are a range of lifestyle factors which can negatively affect both a person's physical
and mental health, and there is increasing evidence that therapeutic lifestyle change can be …

[HTML][HTML] Nutritional therapy can reduce the burden of depression management in low income countries: A review

MB Ekong, CF Iniodu - IBRO Neuroscience Reports, 2021 - Elsevier
Depression is a serious mental and mood disorder with global health and economic burden.
This burden may be overwhelming in low income countries, although there are insufficient …

Gender-affirming treatment of gender dysphoria in youth: a perfect storm environment for the placebo effect—the implications for research and clinical practice

A Clayton - Archives of Sexual Behavior, 2023 - Springer
In the last decade, there has been a rapid increase in the numbers of young people with
gender dysphoria (GD youth) presenting to health services (Kaltiala et al., 2020). There has …

On the treatment effect heterogeneity of antidepressants in major depression: A Bayesian meta-analysis and simulation study

C Volkmann, A Volkmann, CA Müller - PloS one, 2020 - journals.plos.org
Background The average treatment effect of antidepressants in major depression was found
to be about 2 points on the 17-item Hamilton Depression Rating Scale, which lies below …

Global prevalence of antidepressant drug utilization in the community: protocol for a systematic review

C Lunghi, M Dugas, J Leclerc, E Poluzzi… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Antidepressant drugs are the most frequently prescribed medication for mental
disorders. They are also used off-label and for non-psychiatric indications. Prescriptions of …