This chapter emphasizes recent progress in the use of baculovirus expression vectors,
especially in regard to applications in agriculture and medicine, and outlines the …

Susceptibility to multiple sclerosis (MS) is associated with the human histocompatibility
leukocyte antigen (HLA)-DR2 haplotype, suggesting that major histocompatibility complex …

Background: Class II major histocompatibility complex (MHC) proteins are cell surface
glycoproteins that bind peptides and present them to T cells as part of the mechanism for …

HLA-DM (DM) facilitates peptide loading of major histocompatibility complex class II
molecules in human cell lines. Mice lacking functional H2-M, the mouse equivalent of DM …

Evidence is presented that suggests a role for transmembrane domain interactions in the
assembly of class II major histocompatibility complex (MHC) molecules. Mutations in the …

HLA-DM catalyzes the release of MHC class II–associated invariant chain–derived peptides
(CLIP) from class II molecules. Recent evidence has suggested that HLA-DO is a negative …

Major histocompatibility complex (MHC) class II–positive cell lines which lack HLA-DM
expression accumulate class II molecules associated with residual invariant (I) chain …

The crystal structure of the human class I MHC molecule HLA-A2 complexed with of an
octameric peptide, Tax8 (LFGYPVYV), from human T cell lymphotrophic virus-1 (HTLV-1) …

Class II major histocompatibility complexes bind peptides in an endosome-like
compartment. When the class II null cell line 721.174 was transfected with class II DR3 …

Major histocompatibility complex (MHC) class II molecules are cell surface proteins that
present peptides to CD4+ T cells. In addition to these wellcharacterized molecules, two other …