Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

With the advances in biomedical technologies, natural products have attracted substantial
public attention in the area of drug discovery. Flavonoids are a class of active natural …

Diabetic nephropathy is manifested in more than 10% of people with diabetes. It is a
common cause of kidney failure and end-stage kidney disease. Understanding of …

Context Novel fasting interventions have gained scientific and public attention. Periodic
fasting has emerged as a dietary modification promoting beneficial effects on metabolic …

Diabetic nephropathy (DN) is a common complication of diabetes mellitus. While there has
been a great advance in our understanding of the pathogenesis of DN, no effective …

Renal tubulointerstitial fibrosis (TIF), characterized by epithelial-to-mesenchymal transition
(EMT) of renal tubular epithelial cells, is the typical pathological alteration in diabetic …

Diabetic kidney disease (DKD) is a common and severe complication of diabetes mellitus. If
left untreated, DKD can advance to end stage renal disease that requires either dialysis or …

Accumulating evidence implicates the histone acetylation-based epigenetic mechanisms in
the pathoetiology of diabetes-associated micro-/macrovascular complications. Diabetic …

Diabetes is one of the leading causes of chronic kidney disease (CKD), and multiple
underlying mechanisms involved in pathogenesis of diabetic nephropathy (DN) have been …

Diabetic kidney disease (DKD) is a severe microvascular complication in patients with
diabetes and is one of the main causes of renal failure. The current clinical treatment …