Quantification of amyloid PET for future clinical use: a state-of-the-art review
Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer's
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …
The amyloid imaging for the prevention of Alzheimer's disease consortium: A European collaboration with global impact
LE Collij, G Farrar, D Valléz García, I Bader… - Frontiers in …, 2023 - frontiersin.org
Background Amyloid-β (Aβ) accumulation is considered the earliest pathological change in
Alzheimer's disease (AD). The Amyloid Imaging to Prevent Alzheimer's Disease (AMYPAD) …
Alzheimer's disease (AD). The Amyloid Imaging to Prevent Alzheimer's Disease (AMYPAD) …
Validation of quantitative assessment of florbetaben PET scans as an adjunct to the visual assessment across 15 software methods
A Jovalekic, N Roé-Vellvé, N Koglin… - European Journal of …, 2023 - Springer
Purpose Amyloid positron emission tomography (PET) with [18F] florbetaben (FBB) is an
established tool for detecting Aβ deposition in the brain in vivo based on visual assessment …
established tool for detecting Aβ deposition in the brain in vivo based on visual assessment …
Visual assessment of [18F]flutemetamol PET images can detect early amyloid pathology and grade its extent
Purpose To investigate the sensitivity of visual read (VR) to detect early amyloid pathology
and the overall utility of regional VR. Methods [18 F] Flutemetamol PET images of 497 …
and the overall utility of regional VR. Methods [18 F] Flutemetamol PET images of 497 …
Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study
I Bader, I Bader, I Lopes Alves, D Vállez García… - Alzheimer's Research & …, 2023 - Springer
Background The mismatch between the limited availability versus the high demand of
participants who are in the pre-dementia phase of Alzheimer's disease (AD) is a bottleneck …
participants who are in the pre-dementia phase of Alzheimer's disease (AD) is a bottleneck …
Regional associations of white matter hyperintensities and early cortical amyloid pathology
L Lorenzini, LT Ansems, I Lopes Alves… - Brain …, 2022 - academic.oup.com
White matter hyperintensities (WMHs) have a heterogeneous aetiology, associated with both
vascular risk factors and amyloidosis due to Alzheimer's disease. While spatial distribution of …
vascular risk factors and amyloidosis due to Alzheimer's disease. While spatial distribution of …
Dynamic 18F-FPCIT PET: quantification of Parkinson disease metabolic networks and nigrostriatal dopaminergic dysfunction in a single imaging session
S Peng, C Tang, K Schindlbeck… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Previous multicenter imaging studies with 18F-FDG PET have established the presence of
motor-related and cognition-related metabolic patterns of Parkinson disease (PD), termed …
motor-related and cognition-related metabolic patterns of Parkinson disease (PD), termed …
Early detection of amyloid load using 18F-florbetaben PET
Background A low amount and extent of Aβ deposition at early stages of Alzheimer's
disease (AD) may limit the use of previously developed pathology-proven composite SUVR …
disease (AD) may limit the use of previously developed pathology-proven composite SUVR …
Impact of nut consumption on cognition across the lifespan
Cognitive health is a life-long concern affected by modifiable risk factors, including lifestyle
choices, such as dietary intake, with serious implications for quality of life, morbidity, and …
choices, such as dietary intake, with serious implications for quality of life, morbidity, and …
Strategies to reduce sample sizes in Alzheimer's disease primary and secondary prevention trials using longitudinal amyloid PET imaging
Background Detecting subtle-to-moderate biomarker changes such as those in amyloid PET
imaging becomes increasingly relevant in the context of primary and secondary prevention …
imaging becomes increasingly relevant in the context of primary and secondary prevention …