[HTML][HTML] Current development of nano-drug delivery to target macrophages

D Cai, W Gao, Z Li, Y Zhang, L Xiao, Y Xiao - Biomedicines, 2022 - mdpi.com
Macrophages are the most important innate immune cells that participate in various
inflammation-related diseases. Therefore, macrophage-related pathological processes are …

[HTML][HTML] Significance of conserved regions in coronavirus spike protein for developing a novel vaccine against SARS-CoV-2 infection

TA Olukitibi, Z Ao, B Warner, R Unat, D Kobasa, X Yao - Vaccines, 2023 - mdpi.com
Over the years, several distinct pathogenic coronaviruses have emerged, including the
pandemic SARS-CoV-2, which is difficult to curtail despite the availability of licensed …

A recombinant VSV-based bivalent vaccine effectively protects against both SARS-CoV-2 and influenza a virus infection

Z Ao, MJ Ouyang, TA Olukitibi, B Warner… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT COVID-19 and influenza are both highly contagious respiratory diseases that
have been serious threats to global public health. It is necessary to develop a bivalent …

Drug delivery to macrophages: A review of nano-therapeutics targeted approach for inflammatory disorders and cancer

M Mukhtar, H Ali, N Ahmed, R Munir… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …

[HTML][HTML] How promising are HIV-1-based virus-like particles for medical applications

SA Martins, J Santos, RDM Silva, C Rosa… - Frontiers in Cellular …, 2022 - frontiersin.org
New approaches aimed at identifying patient-specific drug targets and addressing unmet
clinical needs in the framework of precision medicine are a strong motivation for researchers …

[HTML][HTML] Oral immunization with rVSV bivalent vaccine elicits protective immune responses, including ADCC, against both SARS-CoV-2 and Influenza A viruses

MJ Ouyang, Z Ao, TA Olukitibi, P Lawrynuik, C Shieh… - Vaccines, 2023 - mdpi.com
COVID-19 and influenza both cause enormous disease burdens, and vaccines are the
primary measures for their control. Since these viral diseases are transmitted through the …

[HTML][HTML] Development and characterization of influenza M2 ectodomain and/or hemagglutinin stalk-based dendritic cell-targeting vaccines

TA Olukitibi, Z Ao, H Azizi, M Mahmoudi… - Frontiers in …, 2022 - frontiersin.org
A universal influenza vaccine is required for broad protection against influenza infection.
Here, we revealed the efficacy of novel influenza vaccine candidates based on Ebola …

[HTML][HTML] Dendritic cells/macrophages-targeting feature of Ebola glycoprotein and its potential as immunological facilitator for antiviral vaccine approach

TA Olukitibi, Z Ao, M Mahmoudi, GA Kobinger, X Yao - Microorganisms, 2019 - mdpi.com
In the prevention of epidemic and pandemic viral infection, the use of the antiviral vaccine
has been the most successful biotechnological and biomedical approach. In recent times …

Development and evaluation of an Ebola virus glycoprotein mucin-like domain replacement system as a new dendritic cell-targeting vaccine approach against HIV-1

Z Ao, L Wang, H Azizi, TA Olukitibi, G Kobinger… - Journal of …, 2021 - Am Soc Microbiol
The development of efficient vaccine approaches against HIV infection remains challenging
in the vaccine field. Here, we developed an Ebola virus envelope glycoprotein (EboGP) …

An overview on macrophage targeting: a promising approach

VD Vemuri, R Kushwaha, G Gowri… - Critical Reviews™ in …, 2023 - dl.begellhouse.com
Macrophages are immuno cells with high flexibility among hematopoietic system.
Macrophages are tangled with many diseases like chronic inflammatory, atherosclerosis …