Tuberculosis (TB) is the major cause of death from infectious diseases around the world,
particularly in HIV infected individuals. TB vaccine design and development have been …

In recent decades, various polymeric carriers with natural or synthetic origin have been
studied for anti-TB drug delivery or vaccination. Despite the advantages of micron-sized …

Background: Tuberculosis (TB) remains a major cause of global morbidity and mortality,
especially in the context of HIV coinfection because immunity is not completely restored …

Mycobacterium tuberculosis is the world's most successful pathogen, having survived over
70,000 years and currently infecting nearly 2 billion people worldwide [1]. With around 9 …

Mycobacterium tuberculosis continues to be one of the most successful pathogens on earth.
Upon inhalation of M. tuberculosis by a healthy individual, the host immune system will …

More than 60 years ago, Swedish biochemist Pehr Edman introduced the first technique for
single peptide sequencing (1). The underlying principle involves a phenylisothiocyanate …

Recently we reported (Mehra et al., 2013), that lung granulomas from Mycobacterium bovis
Bacille Calmette–Guérin (BCG)-vaccinated cynomolgus macaques exhibit upon challenge …

Pulmonary TB remains a leading global health issue, but the current Bacille Calmette-
Guérin (BCG) vaccine fails to control it effectively. Much effort has gone into developing safe …

Despite efforts to develop effective treatments and vaccines, Mycobacterium tuberculosis
(Mtb), particularly pulmonary Mtb, continues to provide major health challenges worldwide …

Background Mycobacterium intracellulare is a major cause of Mycobacterium avium
complex lung disease in many countries. Molecular studies have revealed several new …