[HTML][HTML] Cancer metabolites: promising biomarkers for cancer liquid biopsy

W Wang, Z Rong, G Wang, Y Hou, F Yang, M Qiu - Biomarker Research, 2023 - Springer
Cancer exerts a multitude of effects on metabolism, including the reprogramming of cellular
metabolic pathways and alterations in metabolites that facilitate inappropriate proliferation of …

[HTML][HTML] The role of NPC1L1 in cancer

R Zhang, J Zeng, W Liu, J Meng, C Wang… - Frontiers in …, 2022 - frontiersin.org
Lipid metabolism appears to play significant roles in the development of cancer. Numerous
studies have shown that the evolution of malignancies, including breast, prostate, and …

Pyroptosis and inflammasomes in cancer and inflammation

JL Wang, SN Hua, HJ Bao, J Yuan, Y Zhao… - MedComm, 2023 - Wiley Online Library
Nonprogrammed cell death (NPCD) and programmed cell death (PCD) are two types of cell
death. Cell death is significantly linked to tumor development, medication resistance, cancer …

Aziridination-Assisted Mass Spectrometry of Nonpolar Sterol Lipids with Isomeric Resolution

E Hirtzel, M Edwards, D Freitas, Z Liu… - Journal of the …, 2023 - ACS Publications
Characterization of nonpolar lipids is crucial due to their essential biological functions and
ability to exist in various isomeric forms. In this study, we introduce the N–H aziridination …

[HTML][HTML] Enhancing Immunotherapy in Ovarian Cancer: The Emerging Role of Metformin and Statins

DL Almeida-Nunes, R Silvestre… - International Journal of …, 2023 - mdpi.com
Ovarian cancer metastization is accompanied by the development of malignant ascites,
which are associated with poor prognosis. The acellular fraction of this ascitic fluid contains …

Preliminary exploration of the anti-ovarian cancer activity of peptides derived from bovine bone collagen hydrolysate and its related mechanisms

H Li, J Wang, B Zhang, Y Guo - International Journal of Biological …, 2024 - Elsevier
Ovarian cancer, a malignant tumor that poses a significant threat to women's health, has
seen a rise in incidence, prompting the urgent need for more effective treatment. This study …

[HTML][HTML] Pre-operative levels of angiopoietin protein-like 3 (ANGPTL3) in women diagnosed with high-grade serous carcinoma of the ovary

E Wong Chong, FH Joncas, P Douville… - Lipids in Health and …, 2024 - Springer
Cancer cells need constant supplies of lipids to survive and grow. Lipid dependence has
been observed in various types of cancer, including high-grade serous ovarian carcinomas …

The role of inflammasomes in ovarian cancer

B da Silva Martins, RSR Junior, TM Pimenta… - Exon …, 2022 - exonpublications.com
Ovarian cancer is a leading cause of gynecological cancer-related deaths in women
worldwide, mainly because of its late diagnosis. In many cases, at the time of diagnosis, the …

[HTML][HTML] Cholesterol Biosynthesis Inhibitor RO 48–8071 Suppresses Growth of Epithelial Ovarian Cancer Cells in Vitro and In Vivo

Y Liang, KP Nephew, SM Hyder - Journal of cancer science and …, 2023 - ncbi.nlm.nih.gov
Methods: Cell viability assays were performed to determine effects of RO 48–8071 on
growth of EOC cells. Aldehyde Dehydrogenase (ALDH) assay was conducted to determine …

[HTML][HTML] Dysregulation of Cholesterol Homeostasis in Ovarian Cancer

Z Qusairy, A Gangloff, SOA Leung - Current Oncology, 2023 - mdpi.com
Cholesterol plays an essential role in maintaining the rigidity of cell membranes and signal
transduction. Various investigations confirmed empirically that the dysregulation of …