Treatment-resistant depression

C Cusin, S Peyda - The Massachusetts general hospital guide to …, 2019 - Springer
Major depression is one of the most common psychiatric disorders, and it often presents in
combination with other medical and psychiatric illnesses. In almost one third of cases, it …

The impact of depression medications on oral antidiabetic drug adherence in patients with diabetes and depression

S Xing, GS Calip, AD Leow, S Kim… - Journal of diabetes and …, 2018 - Elsevier
Aims To compare adherence and persistence to oral antidiabetic drugs (OAD) between
patients who are new users of second generation antipsychotics (SGA) versus new users of …

Evaluating the efficacy and moderators of algorithm-guided antidepressant treatments of major depressive disorder

H Zhang, Z Wu, L Cao, Y Su, F Wang, W Hong… - Journal of Affective …, 2022 - Elsevier
Background In spite of numerous options, the most efficacious treatment for major
depressive disorder (MDD) remains elusive. Algorithm-guided treatments (AGTs) are …

[HTML][HTML] A Post-Authorization Safety Study of Quetiapine as Antidepressant Treatment in Sweden: Nested Case–Control Analyses of Select Outcomes

J Reutfors, P Brenner, B Brody, H Wray, M Andersen… - Drug safety, 2020 - Springer
Introduction This post-authorization safety study (PASS) was a commitment to the European
Medicines Agency. Objective This PASS investigated quetiapine as antidepressant …

[HTML][HTML] Medication adherence, health care utilization, and costs in patients with major depressive disorder initiating adjunctive atypical antipsychotic treatment

MS Broder, M Greene, T Yan, E Chang, A Hartry… - Clinical Therapeutics, 2019 - Elsevier
Purpose The purpose of this study was to compare medication adherence, health care
utilization, and cost among patients receiving adjunctive treatment for major depressive …

The choice of either quetiapine or aripiprazole as augmentation treatment in a European naturalistic sample of patients with major depressive disorder

L Bartova, G Fugger, M Dold, A Kautzky… - International Journal …, 2022 - academic.oup.com
Background Augmentation with second-generation antipsychotics (SGAs) represents an
evidence-based psychopharmacotherapeutic strategy recommended in case of insufficient …

Systems pharmacology uncovers serotonergic pathway mediated psychotherapeutic effects of Lonicerae Japonicae Flos

Z Wu, L Chen, Z Guo, K Li, Y Fu, J Zhu, X Chen… - Journal of Functional …, 2019 - Elsevier
Psychiatric disorders have become the biggest cause of non-fatal health burden and are the
major contributor to suicide worldwide. The currently limitations of standard psychotherapy …

Treatment-resistant depression among US military veterans

RG Lande - Veteran Psychiatry in the US: Optimizing Clinical …, 2019 - Springer
Major depressive disorder is one of the most common behavioral disorders and with
aggressive treatment roughly two-thirds of individuals will achieve remission. The remaining …

Characteristics of patients with major depressive disorder switching SSRI/SNRI therapy compared with those augmenting with an atypical antipsychotic in a real-world …

DM Kern, MS Cepeda… - Current Medical …, 2021 - Taylor & Francis
Background Following a partial response of first-line antidepressant therapy for the
treatment of major depressive disorder (MDD), there is a choice to augment treatment with …

Discovering interactions in augmentation strategies: Impact of duloxetine on the metabolism of aripiprazole

T Margraff, G Schoretsanitis, I Neuner… - Basic & Clinical …, 2023 - Wiley Online Library
Objective We aimed to unravel potential pharmacokinetic interactions between aripiprazole
and duloxetine. Methods Plasma concentrations of aripiprazole in two groups of 78 patients …