Outer membrane vesicles (OMVs) produced by gram‐negative bacteria: structure, functions, biogenesis, and vaccine application
N Furuyama, MP Sircili - BioMed Research International, 2021 - Wiley Online Library
Gram‐negative bacteria produce outer membrane vesicles (OMVs) with 10 to 300 nm of
diameter. The contribution of OMVs to bacterial pathogenesis is a topic of great interest, and …
diameter. The contribution of OMVs to bacterial pathogenesis is a topic of great interest, and …
[HTML][HTML] Beyond HIV infection: neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases
The interactions between chemokine receptors and their ligands may affect susceptibility to
infectious diseases as well as their clinical manifestations. These interactions mediate both …
infectious diseases as well as their clinical manifestations. These interactions mediate both …
Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization
JL Konopka-Anstadt, R Campagnoli, A Vincent, J Shaw… - npj Vaccines, 2020 - nature.com
Enormous progress has been made in global efforts to eradicate poliovirus, using live-
attenuated Sabin oral poliovirus vaccine (OPV). However, as the incidence of disease due to …
attenuated Sabin oral poliovirus vaccine (OPV). However, as the incidence of disease due to …
Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic
MR Loffredo, L Nencioni, ML Mangoni… - Journal of Peptide …, 2024 - Wiley Online Library
The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2) has highlighted how urgent and necessary the discovery of new antiviral …
CoV‐2) has highlighted how urgent and necessary the discovery of new antiviral …
The elimination of human African trypanosomiasis is in sight: Report from the third WHO stakeholders meeting on elimination of gambiense human African …
MP Barrett - PLoS neglected tropical diseases, 2018 - journals.plos.org
In 2012, the World Health Organisation (WHO) set out a roadmap for the control, elimination,
or eradication of 17 neglected tropical diseases by 2020 [1]. Many were skeptical about the …
or eradication of 17 neglected tropical diseases by 2020 [1]. Many were skeptical about the …
To be, or not to be… Guillain-Barré Syndrome
Abstract Guillain-Barré Syndrome (GBS) is currently the most frequent cause of acute flaccid
paralysis on a global scale, being an autoimmune disorder wherein demyelination of the …
paralysis on a global scale, being an autoimmune disorder wherein demyelination of the …
Hepatitis C virus vaccine research: time to put up or shut up
AS Hartlage, A Kapoor - Viruses, 2021 - mdpi.com
Unless urgently needed to prevent a pandemic, the development of a viral vaccine should
follow a rigorous scientific approach. Each vaccine candidate should be designed …
follow a rigorous scientific approach. Each vaccine candidate should be designed …
Second-generation live-attenuated Candid# 1 vaccine virus resists reversion and protects against lethal Junín virus infection in guinea pigs
BB Gowen, BT Hickerson, J York, JB Westover… - Journal of …, 2021 - Am Soc Microbiol
Live-attenuated virus vaccines are highly effective in preventing viral disease but carry
intrinsic risks of residual virulence and reversion to pathogenicity. The classically derived …
intrinsic risks of residual virulence and reversion to pathogenicity. The classically derived …
The early evolution of oral poliovirus vaccine is shaped by strong positive selection and tight transmission bottlenecks
AL Valesano, M Taniuchi, WJ Fitzsimmons, MO Islam… - Cell host & …, 2021 - cell.com
The emergence of circulating vaccine-derived polioviruses through evolution of the oral
polio vaccine (OPV) poses a significant obstacle to polio eradication. Understanding the …
polio vaccine (OPV) poses a significant obstacle to polio eradication. Understanding the …
Enterovirus detection in different regions of Madagascar reveals a higher abundance of enteroviruses of species C in areas where several outbreaks of vaccine …
R Razafindratsimandresy, ML Joffret… - BMC Infectious …, 2022 - Springer
Background Poliomyelitis outbreaks due to pathogenic vaccine-derived polioviruses
(VDPVs) are threatening and complicating the global polio eradication initiative. Most of …
(VDPVs) are threatening and complicating the global polio eradication initiative. Most of …