In the ever evolving landscape of systemic immune mediated diseases, an increased
awareness regarding the associated cardiovascular system impairment has been noted in …

Introduction The symptom of dry mouth has multiple potential etiologies and can be a
diagnostic clue to the presence of common systemic diseases encountered in rheumatology …

Primary Sjögren's syndrome (pSS) patients exhibit enhanced degradation of the salivary
epithelium initially through MMP9 overexpression. We assessed the expression of MMP9 …

The purpose of this trial was to clinically assess the effect and safety of Adipose Tissue-
derived Stem Cells (ADSCs) treatment on primary Sjogren's Syndrome (pSS). In this 6 …

Autoimmune diseases are caused by a dysfunction of the acquired immune system. In a
subset of autoimmune diseases, B cells escaping immune tolerance present autoantigen …

Primary Sjogren syndrome (pSS) is the second most common autoimmune disorder
worldwide, which, in the worst scenario, progresses to Non-Hodgkin Lymphoma (NHL) …

Background Recent studies have proven the existence of distinct monocyte subsets, which
play a significant role in the development of some rheumatic diseases such as systemic …

Primary Sjögren's syndrome (pSS) is an autoimmune disease represented by exocrine
gland epithelial cell lesions. However, the mechanism underlying these lesions remains …

Background: Modified Zengye Decoction (MZD), a traditional Chinese medicine, is an
effective treatment for patients with primary Sjögren's syndrome (pSS). Purpose: To evaluate …

Sjögren's disease (SjD) causes localised and systemic inflammation due to autoantibody
production against intracellular proteins, such as TRIM21/Ro52. TRIM21 is an E3 ubiquitin …