The ability to study cellular physiology using photosensitive, genetically encoded molecules
has profoundly transformed neuroscience. The modern optogenetic toolbox includes …

Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …

Biological systems assemble living materials that are autonomously patterned, can self-
repair and can sense and respond to their environment. The field of engineered living …

Arabidopsis thaliana cryptochrome 2 (At CRY2), a light-sensitive photosensory protein, was
previously adapted for use in controlling protein–protein interactions through light …

Active nucleocytoplasmic transport is a key mechanism underlying protein regulation in
eukaryotes. While nuclear protein import can be controlled in space and time with a portfolio …

The ability to independently control the expression of different genes is important for
quantitative biology. Using budding yeast, we characterize GAL1pr, GALL, MET3pr, CUP1pr …

Phytochromes are red/far-red reversible photoreceptors essential for plant growth and
development. Phytochrome signaling is mediated by the physiologically active far-red …

Light has emerged as a control input for biological systems due to its precise spatiotemporal
resolution. The limited toolset for light control in bacteria motivated us to develop a light …

Highlights•Two dynamic control modalities have been developed for metabolic
engineering.•The most common modality uses two phases of fermentation: growth and …

In optogenetics, researchers use light and genetically encoded photoreceptors to control
biological processes with unmatched precision. However, outside of neuroscience, the …