Prognostic factors in organ confined prostate cancer will reflect survival after surgical radical
prostatectomy. Gleason score, tumour volume, surgical margins and Ki-67 index have the …

It is now well established that cancer cells exhibit a number of genetic defects in the
machinery that governs programmed cell death and that sabotage of apoptosis is one of the …

The androgen receptor (AR) plays a key role in prostate cancer development, as well as its
treatments, even for the hormone-refractory state. Here, we report that an earlier described …

Metastatic prostate cancer is a terminal disease, and the development of reliable prognostic
tools and more effective therapy is critically important for improved disease survival and …

ABSTRACT N6-Methyladenosine (m6A) is the most abundant modifications in human
messenger RNAs (mRNAs). This study aimed at investigating the function and mechanism …

Increasing evidence indicates that immunoglobulins are important for the regulation of
various cancers including prostate cancer (PCa). However, the underlying mechanisms of …

Background and Objectives The GSTM1, GSTT1 and GSTP1 polymorphisms might be
involved in inactivation of procarcinogens that contribute to the genesis and progression of …

Background Global DNA methylation alterations are hallmarks of cancer. The tumor-
suppressive TET enzymes, which are involved in DNA demethylation, are decreased in …

The aim of the present study was to analyze the molecular mechanisms involved in blocking
the signaling pathway and the effects of this on the progression of prostate cancer (CaP) …

Na+/I− symporter (NIS)-mediated radioiodide uptake (RAIU) serves as the basis for targeted
ablation of thyroid cancer remnants. However, many patients with thyroid cancer have …