[HTML][HTML] Current progress in gene delivery technology based on chemical methods and nano-carriers

L Jin, X Zeng, M Liu, Y Deng, N He - Theranostics, 2014 - ncbi.nlm.nih.gov
Gene transfer methods are promising in the field of gene therapy. Current methods for gene
transfer include three major groups: viral, physical and chemical methods. This review …

Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease

G De Rubis, KR Paudel, L Corrie, S Mehndiratta… - Naunyn-Schmiedeberg's …, 2023 - Springer
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …

[HTML][HTML] Molecular machineries of pH dysregulation in tumor microenvironment: potential targets for cancer therapy

MR Asgharzadeh, J Barar, MM Pourseif… - BioImpacts …, 2017 - ncbi.nlm.nih.gov
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Introduction: Cancer is an intricate disorder/dysfunction of cells that can be defined as a …

Vectors and strategies for nonviral cancer gene therapy

J Pahle, W Walther - Expert Opinion on Biological Therapy, 2016 - Taylor & Francis
Introduction: This review presents recent developments in the use of nonviral vectors and
transfer technologies in cancer gene therapy. Tremendous progress has been made in …

Nanocarriers in gene therapy: a review

H Xu, Z Li, J Si - Journal of biomedical nanotechnology, 2014 - ingentaconnect.com
With its rapid development in the past few decades, gene therapy has shown potential for
use as a standard clinical intervention for the treatment of several conditions, including …

Solid lipid-based nanocarriers as efficient targeted drug and gene delivery systems

JEN Dolatabadi, Y Omidi - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
Most of the active pharmaceutical ingredients are often prone to display low bioavailability,
biological degradation and inadvertent intrinsic side effects. To circumvent such obstacles …

[HTML][HTML] Impacts of quantum dots in molecular detection and bioimaging of cancer

O Mashinchian, M Johari-Ahar, B Ghaemi… - BioImpacts …, 2014 - ncbi.nlm.nih.gov
Introduction: A number of assays have so far been exploited for detection of cancer
biomarkers in various malignancies. However, the expression of cancer biomarker (s) …

Aptamer-conjugated mesoporous silica nanoparticles for simultaneous imaging and therapy of cancer

S Vandghanooni, J Barar, M Eskandani… - TrAC Trends in Analytical …, 2020 - Elsevier
Mesoporous silica nanoparticles (MSNs) possess wide requirements for successful drug
delivery, due to their superior physicochemical properties such as the well-organized porous …

Advanced nanoscale delivery systems for mRNA-based vaccines

M Mobasher, R Ansari, AM Castejon, J Barar… - Biochimica et Biophysica …, 2024 - Elsevier
The effectiveness of messenger RNA (mRNA) vaccines, especially those designed for
COVID-19, relies heavily on sophisticated delivery systems that ensure efficient delivery of …

Tamoxifen loaded folic acid armed PEGylated magnetic nanoparticles for targeted imaging and therapy of cancer

MH Majd, D Asgari, J Barar, H Valizadeh, V Kafil… - Colloids and Surfaces B …, 2013 - Elsevier
Magnetic nanoparticles (MNPs) have been widely used as drug delivery nanosystems and
contrast agent for imaging and detection. To engineer multifunctional nanomedicines for …