[图书][B] The Human Psyche: The GIFFORD Lectures University of Edinburgh 1978–1979

JC Eccles - 2012 - books.google.com
In February and March 1978 I delivered my first series of Gifford Lectures in the University of
Edinburgh. These lectures have been published under the title The Human Mystery. The …

Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA

AA Alhaider, SZ Lei, GL Wilcox - Journal of Neuroscience, 1991 - Soc Neuroscience
Although 5-HT is clearly involved in spinal analgesia, its mode of action remains obscure,
perhaps because it has multiple and often opposing effects mediated by its multiple receptor …

Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure

MH Ossipov, J Lai, T King… - … Original Research on …, 2005 - Wiley Online Library
The opioid analgesics, commonly exemplified by morphine, represent the best option for the
treatment of severe pain and for the management of chronic pain states, of both malignant …

The organization and function of endogenous antinociceptive systems

J Sandkühler - Progress in neurobiology, 1996 - Elsevier
Much progress has been made the understanding of endogenous pain controlling systems.
Recently, new concepts and ideas which are derived from neurobiology, chaos research …

Effect of peppermint and eucalyptus oil preparations on neurophysiological and experimental algesimetric headache parameters

H Göbel, G Schmidt, D Soyka - Cephalalgia, 1994 - Wiley Online Library
The effects of peppermint oil and eucalyptus oil preparations on neurophysiological,
psychological and experimental algesimetric parameters were investigated in 32 healthy …

Spinal neurons that possess the substance P receptor are required for the development of central sensitization

SG Khasabov, SD Rogers, JR Ghilardi… - Journal of …, 2002 - Soc Neuroscience
In previous studies, we have shown that loss of spinal neurons that possess the substance P
receptor (SPR) attenuated pain and hyperalgesia produced by capsaicin, inflammation, and …

Antinociceptive and nociceptive actions of opioids

MH Ossipov, J Lai, T King, TW Vanderah… - Journal of …, 2004 - Wiley Online Library
Although the opioids are the principal treatment options for moderate to severe pain, their
use is also associated with the development of tolerance, defined as the progressive need …

Sex differences in μ-opioid receptor expression in the rat midbrain periaqueductal gray are essential for eliciting sex differences in morphine analgesia

DR Loyd, X Wang, AZ Murphy - Journal of neuroscience, 2008 - Soc Neuroscience
Opioid-based narcotics are the most widely prescribed therapeutic agent for the alleviation
of persistent pain; however, it is becoming increasingly clear that morphine is significantly …

Stress-induced analgesia: neural and hormonal determinants

RJ Bodnar, DD Kelly, M Brutus, M Glusman - … & Biobehavioral Reviews, 1980 - Elsevier
Extensive evidence has indicated that distinct neural systems specifically designed to inhibit
sensitivity to painful stimuli exist. Recent advances suggest that the endorphins, enkephalins …

Direct evidence that spinal serotonin and noradrenaline terminals mediate the spinal antinociceptive effects of morphine in the periaqueductal gray.

TL Yaksh - Brain research, 1979 - psycnet.apa.org
Reports a series of experiments in rats, demonstrating that (a) inhibition of spinal function by
periaqueductal gray (PAG) morphine associated with antinociception is mediated by the …