Background White matter hyperintensities are an important marker of cerebral small vessel
disease. This disease burden is commonly described as hyperintense areas in the cerebral …

In recent years, Alzheimer's disease (AD) has been a serious threat to human health.
Researchers and clinicians alike encounter a significant obstacle when trying to accurately …

Introduction White matter hyperintensities (WMH) are often described in Alzheimer's disease
(AD), but their topography and specific relationships with cognition remain unclear. Methods …

White matter hyperintensities (WMH), frequently seen in older adults, are usually considered
vascular lesions, and participate in the vascular contribution to cognitive impairment and …

Little is known about a longitudinal decline in white matter microstructure and its
associations with cognition in preclinical dementia. Longitudinal diffusion tensor imaging …

Deep learning (DL) on brain magnetic resonance imaging (MRI) data has shown excellent
performance in differentiating individuals with Alzheimer's disease (AD). However, the value …

It remains unclear to what extent cerebrovascular burden relates to amyloid beta (Aβ)
deposition, neurodegeneration, and cognitive dysfunction in mixed disease populations with …

Objective To investigate the correlation between specific fiber tracts and grip strength and
cognitive function in patients with Alzheimer's disease (AD) by fixel-based analysis (FBA) …

Background White matter hyperintensities (WMH), a biomarker of small vessel disease, are
often found in Alzheimer's disease (AD) and their advanced detection and quantification can …

The default mode network (DMN) typically exhibits deactivations during demanding tasks
compared to periods of relative rest. In functional magnetic resonance imaging (fMRI) …