Molecular mechanisms of the cardiovascular protective effects of polyphenols
R Andriantsitohaina, C Auger, T Chataigneau… - British Journal of …, 2012 - cambridge.org
Epidemiological studies have reported a greater reduction in cardiovascular risk and
metabolic disorders associated with diets rich in polyphenols. The antioxidant effects of …
metabolic disorders associated with diets rich in polyphenols. The antioxidant effects of …
Chemistry and pharmacological actions of delphinidin, a dietary purple pigment in anthocyanidin and anthocyanin forms
Anthocyanins are naturally occurring water-soluble flavonoids abundantly present in fruits
and vegetables. They are polymethoxyderivatives of 2-phenyl-benzopyrylium or flavylium …
and vegetables. They are polymethoxyderivatives of 2-phenyl-benzopyrylium or flavylium …
Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway
M Mu, S Zuo, RM Wu, KS Deng, S Lu… - Drug design …, 2018 - Taylor & Francis
Purpose Liver fibrosis is a worldwide health issue. Development of effective new drugs for
treatment of this disease is of great importance. This study investigated the therapeutic …
treatment of this disease is of great importance. This study investigated the therapeutic …
Myricitrin exhibits antioxidant, anti-inflammatory and antifibrotic activity in carbon tetrachloride-intoxicated mice
R Domitrović, K Rashed, O Cvijanović… - Chemico-biological …, 2015 - Elsevier
Abstract Myricetin-3-O-α-rhamnoside (myricitrin) is a naturally occurring phenolic compound
which possesses antioxidant and anti-inflammatory activity. The aim of this study was to …
which possesses antioxidant and anti-inflammatory activity. The aim of this study was to …
Hepatoprotective activity of berberine is mediated by inhibition of TNF-α, COX-2, and iNOS expression in CCl4-intoxicated mice
This study investigated the protective effects of isoquinoline alkaloid berberine on the CCl4-
induced hepatotoxicity in mice. Berberine was administered as a single dose at 5 and …
induced hepatotoxicity in mice. Berberine was administered as a single dose at 5 and …
Human diet‐derived polyphenolic compounds and hepatic diseases: From therapeutic mechanisms to clinical utilization
Q Hu, W Zhang, F Wei, M Huang, M Shu… - Phytotherapy …, 2024 - Wiley Online Library
This review focuses on the potential ameliorative effects of polyphenolic compounds derived
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …
Differential hepatoprotective mechanisms of rutin and quercetin in CCl4-intoxicated BALB/cN mice
Aim: To investigate the mechanisms underlying the protective effects of quercetin-rutinoside
(rutin) and its aglycone quercetin against CCl 4-induced liver damage in mice. Methods …
(rutin) and its aglycone quercetin against CCl 4-induced liver damage in mice. Methods …
Rosmarinic acid ameliorates acute liver damage and fibrogenesis in carbon tetrachloride-intoxicated mice
R Domitrović, M Škoda, VV Marchesi… - Food and chemical …, 2013 - Elsevier
The aim of this study was to investigate the therapeutic potential of rosmarinic acid (RA), a
natural phenolic, in the treatment of acute liver toxicity. RA at 10, 25 and 50mg/kg was …
natural phenolic, in the treatment of acute liver toxicity. RA at 10, 25 and 50mg/kg was …
Flavonoids-mediated SIRT1 signaling activation in hepatic disorders
The prevalence of various hepatic diseases increases dramatically worldwide and regarded
as a serious health problem. Sirtuins are one of the main strategic controllers of different …
as a serious health problem. Sirtuins are one of the main strategic controllers of different …
[HTML][HTML] Evaluation of berberine efficacy in reducing the effects of aflatoxin B1 and ochratoxin A added to male broiler rations
P Malekinezhad, LE Ellestad, N Afzali, SH Farhangfar… - Poultry Science, 2021 - Elsevier
Many types of mycotoxins are found in food sources contaminated with fungi, and if these
are ingested in large quantities or over a long period, they can affect the health of humans …
are ingested in large quantities or over a long period, they can affect the health of humans …