Bifidobacterium longum: protection against inflammatory bowel disease

S Yao, Z Zhao, W Wang, X Liu - Journal of immunology …, 2021 - Wiley Online Library
The prevalence of inflammatory bowel disease (IBD), which includes ulcerative colitis (UC)
and Crohn's disease (CD), increases gradually worldwide in the past decades. IBD is …

The immune system throws its traps: cells and their extracellular traps in disease and protection

F Conceição-Silva, CSM Reis, PM De Luca… - Cells, 2021 - mdpi.com
The first formal description of the microbicidal activity of extracellular traps (ETs) containing
DNA occurred in neutrophils in 2004. Since then, ETs have been identified in different …

Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound

R Roy, J Zayas, SK Singh, K Delgado, SJ Wood… - Elife, 2022 - elifesciences.org
Infection is a major co-morbidity that contributes to impaired healing in diabetic wounds.
Although impairments in diabetic neutrophils have been blamed for this co-morbidity, what …

Leishmaniasis: immune cells crosstalk in macrophage polarization

FS Almeida, SER Vanderley, FC Comberlang… - Tropical Medicine and …, 2023 - mdpi.com
Leishmaniasis is a complex infectious parasitic disease caused by protozoa of the genus
Leishmania, belonging to a group of neglected tropical diseases. It establishes significant …

[HTML][HTML] Infections and immunity: associations with obesity and related metabolic disorders

A Ray, MJL Bonorden, R Pandit… - … of Pathology and …, 2023 - synapse.koreamed.org
About one-fourth of the global population is either overweight or obese, both of which
increase the risk of insulin resistance, cardiovascular diseases, and infections. In obesity …

Unrevealing the Mystery of Latent Leishmaniasis: What Cells Can Host Leishmania?

A Valigurová, I Kolářová - Pathogens, 2023 - mdpi.com
Leishmania spp.(Kinetoplastida) are unicellular parasites causing leishmaniases, neglected
tropical diseases of medical and veterinary importance. In the vertebrate host, Leishmania …

Molecular-level strategic goals and repressors in Leishmaniasis–Integrated data to accelerate target-based heterocyclic scaffolds

M Abirami, BK Kumar, S Dey, S Johri… - European Journal of …, 2023 - Elsevier
Leishmaniasis is a complex of neglected tropical diseases caused by various species of
leishmanial parasites that primarily affect the world's poorest people. A limited number of …

The c-MET receptor tyrosine kinase contributes to neutrophil-driven pathology in cutaneous leishmaniasis

K Passelli, B Prat-Luri, M Merlot, M Goris… - PLoS …, 2022 - journals.plos.org
Neutrophils are the first line of defence against invading pathogens. Although neutrophils
are well-known professional killers, some pathogens including Leishmania (L.) parasites …

Neutrophil-mediated hypoxia drives pathogenic CD8 T cell responses in cutaneous leishmaniasis

EA Fowler, CF Amorim, K Mostacada… - The Journal of …, 2024 - Am Soc Clin Investig
Cutaneous leishmaniasis caused by Leishmania parasites exhibits a wide range of clinical
manifestations. Although parasites influence disease severity, cytolytic CD8 T cell responses …

Hide-and-seek: A game played between parasitic protists and their hosts

I Kolářová, A Valigurová - Microorganisms, 2021 - mdpi.com
After invading the host organism, a battle occurs between the parasitic protists and the host's
immune system, the result of which determines not only whether and how well the host …