[HTML][HTML] NMR spectroscopy for metabolomics research

AH Emwas, R Roy, RT McKay, L Tenori, E Saccenti… - Metabolites, 2019 - mdpi.com
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

[HTML][HTML] Recommended strategies for spectral processing and post-processing of 1D 1H-NMR data of biofluids with a particular focus on urine

AH Emwas, E Saccenti, X Gao, RT McKay… - Metabolomics, 2018 - Springer
Abstract 1 H NMR spectra from urine can yield information-rich data sets that offer important
insights into many biological and biochemical phenomena. However, the quality and utility …

[HTML][HTML] NMR as a “gold standard” method in drug design and discovery

AH Emwas, K Szczepski, BG Poulson, K Chandra… - Molecules, 2020 - mdpi.com
Studying disease models at the molecular level is vital for drug development in order to
improve treatment and prevent a wide range of human pathologies. Microbial infections are …

Recommendations and standardization of biomarker quantification using NMR-based metabolomics with particular focus on urinary analysis

AH Emwas, R Roy, RT McKay, D Ryan… - Journal of proteome …, 2016 - ACS Publications
NMR-based metabolomics has shown considerable promise in disease diagnosis and
biomarker discovery because it allows one to nondestructively identify and quantify large …

Emerging non-destructive methods for quality and safety monitoring of spices

N Modupalli, M Naik, CK Sunil, V Natarajan - Trends in Food Science & …, 2021 - Elsevier
Background The growing concerns about food quality and safety among consumers have
increased the need for food authentication, which can be a powerful tool to combat different …

[HTML][HTML] Metabolomics: the stethoscope for the twenty-first century

H Ashrafian, V Sounderajah, R Glen, T Ebbels… - Medical Principles and …, 2021 - karger.com
Metabolomics encompasses the systematic identification and quantification of all metabolic
products in the human body. This field could provide clinicians with novel sets of diagnostic …

Metabolic biomarkers in cancer

K Szczepski, I Al-Younis, M Dhahri, JI Lachowicz… - Metabolomics, 2023 - Elsevier
Over the course of years healthcare systems have utilized various “-omics” approaches to
prognose, diagnose, and evaluate the treatment efficacy of cancer diseases. Metabolomics …

[HTML][HTML] Anti-cancer agents in Saudi Arabian herbals revealed by automated high-content imaging

D Hajjar, S Kremb, S Sioud, AH Emwas, CR Voolstra… - PLoS …, 2017 - journals.plos.org
Natural products have been used for medical applications since ancient times. Commonly,
natural products are structurally complex chemical compounds that efficiently interact with …

Imbalance in amino acid and purine metabolisms at the hypothalamus in inflammation-associated depression by GC-MS

Y Wu, Y Li, Y Jia, C Wei, H Xu, R Guo, Y Li, J Jia… - Molecular …, 2017 - pubs.rsc.org
Hypothalamic dysfunction is a key factor in depression; increasing evidence highlights
neuroinflammation abnormalities as well as imbalances in neurotransmitters and the …

[HTML][HTML] Qualitative and Quantitative Mass Spectrometry in Salivary Metabolomics and Proteomics

P Grocholska, M Kowalska, R Bąchor - Metabolites, 2023 - mdpi.com
The metabolomics and proteomics analysis of saliva, an excellent biofluid that is a rich
source of biological compounds, allows for the safe and frequent screening of drugs, their …