Biomarkers, also known as biological markers, are substances like transcripts,
deoxyribonucleic acid (DNA), genes, proteins, and metabolites that indicate whether a …

Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …

Background AlkB homolog 5 (ALKBH5) is a N6-methyladenosine (m6A) demethylase
associated with the development, growth, and progression of multiple cancer types …

Abstract Background Discoidin, CUB, and LCCL domain-containing type I (DCBLD1) is
identified as an oncogene involved in multiple regulation of tumor progression, but specific …

Background: Cellular senescence is a novel hallmark of cancer associated with patient
outcomes and tumor immunotherapy. However, the value of cellular senescence-related …

Simple Summary Pancreatic cancer (PCa) is a highly aggressive and deadly form of cancer
with a low five-year survival rate. This paper explores the role of pharmacologic …

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer,
characterized by high tumor heterogeneity and a poor prognosis. Inter-and intra-tumoral …

Objective: Pancreatic cancer is a highly lethal malignancy globally. This study aimed to
probe and validate immune-related prognostic mRNAs as therapeutic targets for pancreatic …

Given the important role of SLC family in essential physiological processes including
nutrient uptake, ion transport, and waste removal, and that their dysregulation was found in …

Gastrointestinal tumors have become a worldwide health problem with high morbidity and
poor clinical outcomes. Chemotherapy and surgery, the main treatment methods, are still far …