Autophagy and Biomaterials: A Brief Overview of the Impact of Autophagy in Biomaterial Applications

L Pirmoradi, S Shojaei, S Ghavami, A Zarepour… - Pharmaceutics, 2023 - mdpi.com
Macroautophagy (hereafter autophagy), a tightly regulated physiological process that
obliterates dysfunctional and damaged organelles and proteins, has a crucial role when …

Autophagy-mediated nanomaterials for tumor therapy

Z Liao, X Liu, D Fan, X Sun, Z Zhang, P Wu - Frontiers in Oncology, 2023 - frontiersin.org
Autophagy is a lysosomal self-degradation pathway that plays an important protective role in
maintaining intracellular environment. Deregulation of autophagy is related to several …

Novel nano-platinum induces autophagy through dual pathways in the treatment of osteosarcoma in cell lines with different P53 expression patterns

J Wang, H Yue, X Huang, M Zhang - Chemical Engineering Journal, 2024 - Elsevier
Background The enhancement of platinum-based chemotherapeutic agents utilizing
nanotechnology holds promise for improving the prognosis of osteosarcoma chemotherapy …

[HTML][HTML] ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter …

X Wang, L Yao, Z Li, J Zhang, M Ruan… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Background: Renal cell carcinoma (RCC) is one of the most common malignant tumours of
the urinary system. However, the aetiology and pathogenesis of RCC remain unclear. The …

Nano-Pt induced mitochondria-dependent apoptosis and cytoprotective autophagy in human NSCLC cells

J Wu, X Huang, Z Xiao, Q Wang, L Mu, S Yang… - Colloids and Surfaces B …, 2023 - Elsevier
Given that currently used classical chemotherapeutic drugs lack the ideal therapeutic effect
and produce severe side effects, platinum nanomaterials (Pt-NMs) have gradually gained …

FGF19 promotes cell autophagy and cisplatin chemoresistance by activating MAPK signaling in ovarian cancer

W Zhu, M Huang, A Thakur, Y Yan, X Wu - PeerJ, 2023 - peerj.com
Background Chemotherapy is one of the primary treatments for ovarian cancer patients.
Autophagy has been linked to chemotherapy resistance in tumor cells. Recent studies have …

Dioscin Impedes Proliferation, Metastasis and Enhances Autophagy of Gastric Cancer Cells via Regulating the USP8/TGM2 Pathway

T Ma, X Ge, J Zhu, C Song, P Wang, J Cai - Molecular Biotechnology, 2023 - Springer
Gastric cancer (GC) is one of the most common cancers worldwide. Dioscin has been shown
to have anti-cancer effects in GC. The aim of this study is to explore a novel mechanism of …

HNF4G increases cisplatin resistance in lung adenocarcinoma via the MAPK6/Akt pathway

J Liang, G Zhao, Y Bian, G Bi, Q Sui, H Zhang, H Shi… - PeerJ, 2023 - peerj.com
HNF4G increases cisplatin resistance in lung adenocarcinoma via the MAPK6/Akt pathway [PeerJ]
Related research Download Share X Facebook Email PEER-REVIEWED HNF4G increases …

[HTML][HTML] Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

X Chu, J Lou, Y Yi, L Zhong… - European Journal of …, 2023 - ncbi.nlm.nih.gov
The mortality and morbidity rates of ovarian cancer (OC) are high, but the underlying
mechanisms of OC have not been characterized. In this study, we determined the role of …

[PDF][PDF] The predictive value of PI3K signaling pathway in ovarian cancer prognosis: a meta-analysis.

R Wei, L Li - European Review for Medical & Pharmacological …, 2024 - europeanreview.org
OBJECTIVE: The aim of the study was to comprehensively assess the clinical significance of
the Phosphoinositide 3-kinase (PI3K) signaling pathway in ovarian cancer patients, we …