Ras homolog gene family, member A (RhoA) and its downstream effector Rho-associated
protein kinase (ROCK) play important roles in multiple cellular processes, but abnormal …

Melanoma and its associated alterations in cellular pathways have been growing areas of
interest in research, especially as specific biological pathways are being elucidated. Some …

Summary Cyclic GMP-AMP synthase (cGAS) senses cytosolic incoming DNA and
consequently activates stimulator of interferon response cGAMP interactor 1 (STING) to …

Proteostasis dysfunction and activation of the unfolded protein response (UPR) are
characteristic of all major neurodegenerative diseases. Nevertheless, although the UPR and …

Clathrin/dynamin-independent endocytosis of ordered plasma membrane domains (ordered
membrane domain endocytosis, OMDE) can be far more powerful than conventional …

Central nervous system (CNS) damage leads to persistent loss of cognition, sensation, and
motor control, and affecting approximately millions of patients. Retention or regain of …

The bacterial exoenzyme C3 transferase (C3) irreversibly inhibits RhoA GTPase leading to
stimulation of axonal outgrowth in injured neurons. C3 has been used successfully in …

Purpose This study compared the expression of the Ras homolog gene family member A
(RhoA) and Rho-associated coiled-coil kinase (ROCK) signaling pathway members in knee …

Ze současných reviews na téma" buněčná signalizace během neuroregenerace" se G-
proteiny opakovaně objevují jako významný zprostředkovatel signálu. Tato práce si …

Zellen stellen als kleinste funktionelle Einheiten die grundlegenden Bausteine lebender
Organismen dar. Ihre Funktionalität beruht dabei auf geordneten, biochemischen …