Role of m6A writers, erasers and readers in cancer

Z Fang, W Mei, C Qu, J Lu, L Shang, F Cao… - … Hematology & Oncology, 2022 - Springer
Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …

Exosomal circular RNAs: a chief culprit in cancer chemotherapy resistance

X Guo, C Gao, DH Yang, S Li - Drug Resistance Updates, 2023 - Elsevier
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …

RNA-binding proteins and cancer metastasis

S Wang, Z Sun, Z Lei, HT Zhang - Seminars in cancer biology, 2022 - Elsevier
RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Tumor-suppressive circRHOBTB3 is excreted out of cells via exosome to sustain colorectal cancer cell fitness

C Chen, H Yu, F Han, X Lai, K Ye, S Lei, M Mai, M Lai… - Molecular Cancer, 2022 - Springer
Abstract Background & Aims To clarify the biological roles, circularization process and
secretion pathway of circRHOBTB3 in colorectal cancer (CRC) progression. Methods We …

CircRNAs in colorectal cancer: potential biomarkers and therapeutic targets

Y Zhang, J Luo, W Yang, WC Ye - Cell death & disease, 2023 - nature.com
Globally, colorectal cancer (CRC) is the third most prevalent cancer and the second leading
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …

RNMFLP: predicting circRNA–disease associations based on robust nonnegative matrix factorization and label propagation

L Peng, C Yang, L Huang, X Chen, X Fu… - Briefings in …, 2022 - academic.oup.com
Circular RNAs (circRNAs) are a class of structurally stable endogenous noncoding RNA
molecules. Increasing studies indicate that circRNAs play vital roles in human diseases …

[HTML][HTML] A Circular RNAs: Emerging roles and new insights in human cancers

Z He, Q Zhu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Circular RNAs (circRNAs) are single-stranded, covalently closed RNA molecules formed by
mRNA exon back-splicing. Although the circRNA functions remain largely unknown, their …

CircRNA-CREIT inhibits stress granule assembly and overcomes doxorubicin resistance in TNBC by destabilizing PKR

X Wang, T Chen, C Li, W Li, X Zhou, Y Li, D Luo… - Journal of hematology & …, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) represent a novel type of regulatory RNA
characterized by high evolutionary conservation and stability. CircRNAs are expected to be …

Extracellular vesicles in colorectal cancer: from tumor growth and metastasis to biomarkers and nanomedications

L Kotelevets, E Chastre - Cancers, 2023 - mdpi.com
Simple Summary Almost all cell types produce extracellular vesicles that, according to their
size, subcellular origin and release pathways, are mainly categorized as exosomes …

LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement

C Zhang, H Wang, Q Liu, S Dai, G Tian, X Wei… - Journal of Experimental …, 2023 - Springer
Background Gastric cancer (GC) is one of the most prevalent malignant tumors of the
digestive system. As a hallmark of cancer, energy-related metabolic reprogramming is …