[HTML][HTML] An updated review on the psychoactive, toxic and anticancer properties of kava

RB Soares, RJ Dinis-Oliveira, NG Oliveira - Journal of clinical medicine, 2022 - mdpi.com
Kava (Piper methysticum) has been widely consumed for many years in the South Pacific
Islands and displays psychoactive properties, especially soothing and calming effects. This …

Potential genotoxic and biological effects of 1, 4 dioxane on different model organisms

FT Demir, E Demir - Current Opinion in Environmental Science & Health, 2023 - Elsevier
A suspected human carcinogen, the compound 1, 4-dioxane (DXN) has been commonly
employed as a solvent in the production of various cleaning applications, cosmetics, dyes …

In vivo effects of 1,4-dioxane on genotoxic parameters and behavioral alterations in Drosophila melanogaster

F Turna Demir - Journal of Toxicology and Environmental Health …, 2022 - Taylor & Francis
Dioxane (DXN) is used as solvent in different consumer products including cosmetics,
paints, surfactants, and waxes. In addition, DXN is released as an unwanted contaminating …

Genotoxic action of bifenthrin nanoparticles and its effect on the development, productivity, and behavior of Drosophila melanogaster

MP Cruces, E Pimentel, LM Vidal… - Journal of Toxicology …, 2023 - Taylor & Francis
Rapid development of nanotechnology, particularly nanoparticles of pesticides, has
facilitated the transformation of traditional agriculture. However, testing their effectiveness is …

Antitumor activity of solamargine in mouse melanoma model: Relevance to clinical safety

RA Furtado, SD Ozelin, NH Ferreira… - Journal of Toxicology …, 2022 - Taylor & Francis
Melanoma is the most aggressive type of skin cancer, and thus it is important to develop new
drugs for its treatment. The present study aimed to examine the antitumor effects of …

[HTML][HTML] A Drosophila model relevant to chemotherapy-related cognitive impairment

M Torre, H Bukhari, V Nithianandam, CA Zanella… - Scientific Reports, 2023 - nature.com
Chemotherapy-related cognitive impairment (CRCI) is a common adverse effect of treatment
and is characterized by deficits involving multiple cognitive domains including memory …

[HTML][HTML] CircRNA-based cervical cancer prognosis model, immunological validation and drug prediction

X Guo, S Chen, S Wang, H Zhang, F Yin, P Guo… - Current …, 2022 - mdpi.com
Background: Cervical cancer (CC) is a common cancer in female, which is associated with
problems like poor prognosis. Circular RNA (circRNA) is a kind of competing endogenous …

[HTML][HTML] Copper (II) Complex Containing 4-Fluorophenoxyacetic Acid Hydrazide and 1, 10-Phenanthroline: A Prostate Cancer Cell-Selective and Low-Toxic Copper (II …

NJS Bontempo, DA Paixão, PMAP Lima, DCT Barros… - Molecules, 2022 - mdpi.com
Prostate Cancer (PCa) is the second leading cause of cancer-related deaths among men
worldwide. The treatment of advanced cases is based on chemotherapy, which lacks …

[HTML][HTML] Protective effect of kavain in meristematic cells of Allium cepa L.

EPDO VALE, MVR Ferreira, BCS Fernandes… - Anais da Academia …, 2022 - SciELO Brasil
Kavain is one of the main kavalactones of Piper methysticum (Piperaceae) with anxiolytic,
analgesic, and antioxidant activities. Therefore, the aim of the study was to evaluate the …

[HTML][HTML] Arrabidaea chica chloroform extract modulates estrogen and androgen receptors on luminal breast cancer cells

DC Brandão, PMAP Lima, IC Martins… - … Medicine and Therapies, 2022 - Springer
Abstract Background Breast Cancer (BC) is the most common cancer in women worldwide
and, although 70% of patients are responsive to selective Estrogen Receptor (ER) …