Managing the immune microenvironment of osteosarcoma: the outlook for osteosarcoma treatment

H Tian, J Cao, B Li, EC Nice, H Mao, Y Zhang… - Bone Research, 2023 - nature.com
Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Genetically Engineering Cell Membrane‐Coated BTO Nanoparticles for MMP2‐Activated Piezocatalysis‐Immunotherapy

Q Tang, S Sun, P Wang, L Sun, Y Wang… - Advanced …, 2023 - Wiley Online Library
Tumor immunotherapy based on immune checkpoint blockade (ICB) still suffers from low
host response rate and non‐specific distribution of immune checkpoint inhibitors, greatly …

Delivering metal ions by nanomaterials: Turning metal ions into drug-like cancer theranostic agents

C Liu, L Guo, Y Wang, J Zhang, C Fu - Coordination Chemistry Reviews, 2023 - Elsevier
Nanomaterials have been extensively used for cancer therapy and diagnosis due to their
designability, multifunctionality, and unique in vivo distribution. Metal ions are increasingly …

Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment

M Xu, S Li - Cancer Letters, 2023 - Elsevier
Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …

Targeting proinflammatory molecules using multifunctional MnO nanoparticles to inhibit breast cancer recurrence and metastasis

Y Zhong, T Li, Y Zhu, J Zhou, TO Akinade, J Lee, F Liu… - ACS …, 2022 - ACS Publications
Photothermal therapy (PTT) is an effective treatment modality that is highly selective for
tumor suppression and is a hopeful alternative to traditional cancer therapy. However, PTT …

Sodium bicarbonate nanoparticles for amplified cancer immunotherapy by inducing pyroptosis and regulating lactic acid metabolism

B Ding, P Zheng, J Tan, H Chen, Q Meng… - Angewandte …, 2023 - Wiley Online Library
Although immunotherapy has a broad clinical application prospect, it is still hindered by low
immune responses and immunosuppressive tumor microenvironment. Herein, a simple and …

The bioengineered and multifunctional nanoparticles in pancreatic cancer therapy: Bioresponisive nanostructures, phototherapy and targeted drug delivery

MJ Saadh, H Baher, Y Li, JL Arias-Gonzáles… - Environmental …, 2023 - Elsevier
The multidisciplinary approaches in treatment of cancer appear to be essential in term of
bringing benefits of several disciplines and their coordination in tumor elimination. Because …

Interrelation between programmed cell death and immunogenic cell death: take antitumor nanodrug as an example

Q Meng, B Ding, P Ma, J Lin - Small Methods, 2023 - Wiley Online Library
Programmed cell death (PCD, mainly including apoptosis, necrosis, ferroptosis, pyroptosis,
and autophagy) and immunogenic cell death (ICD), as important cell death mechanisms, are …

Ultrasmall zirconium carbide nanodots for synergistic photothermal-radiotherapy of glioma

M Yin, X Chen, Q Guo, L Xiao, P Gao, D Zang, J Dong… - Nanoscale, 2022 - pubs.rsc.org
Glioma is characterized by highly invasive, progressive, and lethal features. In addition,
conventional treatments have been poorly effective in treating glioma. To overcome this …