Viral infections are a common cause of morbidity worldwide. The emergence of Coronavirus
Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel …

Abstract Purpose of Review Deep tissue HIV reservoirs, especially within the central
nervous system (CNS), are understudied due to the challenges of sampling brain, spinal …

Head and neck cancer, one of the most commonly prevalent malignancies globally is a
complex category of tumours that comprises cancers of the oral cavity, pharynx, and larynx …

Since the identification of sickle cell trait as a heritable form of resistance to malaria,
candidate gene studies, linkage analysis paired with sequencing, and genome-wide …

In the early 2000s, novel humanized mouse models based on the transplantation of human
hematopoietic stem and progenitor cells (HSPCs) into immunocompromised mice were …

Abstract Human immunodeficiency virus (HIV)-1 infection is an important public health
problem worldwide. After primary HIV-1 infection, transcribed HIV-1 DNA is integrated into …

In the absence of antiviral therapy, HIV-1 infection progresses to a wide spectrum of clinical
manifestations that are the result of an entangled contribution of host, immune and viral …

Background Antiretroviral therapy has led to AIDS being a chronic disease. Nevertheless,
the presence of constantly emerging drug resistance mutations poses a challenge to clinical …

Combination antiretroviral therapy (cART) effectively blocks HIV replication but cannot
completely eliminate HIV from the body mainly due to establishment of a viral reservoir. To …

Chemokines are cytokines whose primary role is cellular activation and stimulation of
leukocyte migration. They perform their various functions by interacting with G protein …