[HTML][HTML] The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy

N Ricard, S Bailly, C Guignabert… - Nature Reviews Cardiology, 2021 - nature.com
Endothelial cells are at the interface between circulating blood and tissues. This position
confers on them a crucial role in controlling oxygen and nutrient exchange and cellular …

[HTML][HTML] The role of macrophages in the pathogenesis of SARS-CoV-2-associated acute respiratory distress syndrome

A Kosyreva, D Dzhalilova, A Lokhonina… - Frontiers in …, 2021 - frontiersin.org
Macrophages are cells that mediate both innate and adaptive immunity reactions, playing a
major role in both physiological and pathological processes. Systemic SARS-CoV-2 …

Immunothrombosis in acute respiratory distress syndrome: cross talks between inflammation and coagulation

F Frantzeskaki, A Armaganidis, SE Orfanos - Respiration, 2017 - karger.com
Acute respiratory distress syndrome (ARDS) is defined as a syndrome of acute onset, with
bilateral opacities on chest imaging and respiratory failure not caused by cardiac failure …

From sepsis to acute respiratory distress syndrome (ARDS): emerging preventive strategies based on molecular and genetic researches

Q Hu, C Hao, S Tang - Bioscience Reports, 2020 - portlandpress.com
A healthy body activates the immune response to target invading pathogens (ie viruses,
bacteria, fungi, and parasites) and avoid further systemic infection. The activation of …

[HTML][HTML] New insights into the immune molecular regulation of the pathogenesis of acute respiratory distress syndrome

CY Yang, CS Chen, GT Yiang, YL Cheng… - International Journal of …, 2018 - mdpi.com
Acute respiratory distress syndrome is an inflammatory disease characterized by dysfunction
of pulmonary epithelial and capillary endothelial cells, infiltration of alveolar macrophages …

[HTML][HTML] Acute respiratory distress syndrome heterogeneity and the septic ARDS subgroup

H Xu, S Sheng, W Luo, X Xu, Z Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is an acute diffuse inflammatory lung injury
characterized by the damage of alveolar epithelial cells and pulmonary capillary endothelial …

[HTML][HTML] A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS

L Reyes, MA Sanchez-Garcia, T Morrison… - Wellcome open …, 2021 - ncbi.nlm.nih.gov
Background: Acute respiratory distress syndrome (ARDS) is a severe critical condition with a
high mortality that is currently in focus given that it is associated with mortality caused by …

[HTML][HTML] Role of neutrophil extracellular traps in COVID-19 progression: an insight for effective treatment

MA Blanch-Ruiz, R Ortega-Luna, G Gómez-García… - Biomedicines, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has resulted in a
pandemic with over 270 million confirmed cases and 5.3 million deaths worldwide. In some …

[HTML][HTML] The impact of SARS-CoV-2 infection on blood coagulation and fibrinolytic pathways: a review of prothrombotic changes caused by COVID-19

M Bahraini, A Dorgalaleh - Seminars in Thrombosis and …, 2022 - thieme-connect.com
The cardinal pathology of coronavirus disease 2019 (COVID-19) is a primary infection of
pulmonary tract cells by severe acute respiratory syndrome coronavirus 2, provoking a local …

Emerging drugs for treating the acute respiratory distress syndrome

TD Shaw, DF McAuley, CM O'Kane - Expert opinion on emerging …, 2019 - Taylor & Francis
Introduction: The acute respiratory distress syndrome (ARDS) is a common and catastrophic
condition, with a high mortality rate and economic burden on society. Despite 50 years of …