Brd4:: Nutm1 fusion gene initiates NUT carcinoma in vivo

D Zheng, AA Elnegiry, C Luo… - Life Science …, 2024 - life-science-alliance.org
NUT carcinoma (NC) is an aggressive cancer with no effective treatment. About 70% of NUT
carcinoma is associated with chromosome translocation events that lead to the formation of …

CDKN2A somatic copy number amplification in normal tissues surrounding gastric carcinoma reduces cancer metastasis risk in droplet digital PCR analysis

L Deng, J Zhou, Y Sun, Y Hu, J Qiao, Z Liu, L Gu, D Lin… - Gastric Cancer, 2024 - Springer
Abstract Background The CDKN2A gene is frequently affected by somatic copy number
variations (SCNVs, including deletions and amplifications [SCNdel and SCNamp]) in the …

Intraductal Implantation of Biliary Neoplasms: A Potential Cause of “Multifocal” Tumors

Y Zen, M Akita, E Florou, T Fukumoto… - The American Journal …, 2024 - journals.lww.com
Multiple biliary tumors rarely develop in patients without underlying chronic hepatobiliary
disease. Those lesions are regarded as multifocal neoplasms if there is no interconnecting …

[HTML][HTML] Inferring Bladder Cancer Evolution from Mucosal Field Effects by Whole-Organ Spatial Mutational, Proteomic, and Metabolomic Mapping

B Czerniak, S Lee, SY Jung, P Kus, J Bondaruk… - Research …, 2024 - ncbi.nlm.nih.gov
Multi-platform mutational, proteomic, and metabolomic spatial mapping was used on the
whole-organ scale to identify the molecular evolution of bladder cancer from mucosal field …

Field Cancerization: A Malignant Transformation

PE Saw, E Song - Tumor Ecosystem: An Ecological View of Cancer …, 2023 - Springer
Mutations in a cell is natural, especially in aging cells. However, among all mutated cells,
only a certain subset could clonally expand, leading to cancer. These cells then influence …

Field Cancerization in Action; A Case of Synchronous Triple Primary Malignancies in the Head and Neck

J Lakshmanan, A Kushwaha, K Raja - … of Otolaryngology and Head & Neck …, 2024 - Springer
Field cancerization is the phenomenon that classically describes the occurrence of multiple
primary malignancies in the head and neck subsites, either synchronous or metachronous …

AVALIAÇÃO DA IMUNOLOCALIZAÇÃO DO RECEPTOR DO FOSFATIDIL INOSITOL-3 (IP3R) EM CARCINOMAS BASOCELULAR E DE CÉLULAS ESCAMOSAS DE …

CR Gruber, TL Skare, AF Giovanini, MF Sigwalt… - 2024 - preprints.scielo.org
Introduction: Non-melanoma skin neoplasms (basal cell carcinoma (BCC) and squamous
cell carcinoma (SCC) form the most common group of all types of neoplasms. Although …

Alexander Partin*, Thomas Brettin, Yitan Zhu, James M. Dolezal, Sara Kochanny, Alexander T. Pearson, Maulik Shukla, Yvonne A. Evrard, James H. Doroshow and …

K Chen, CM Svensson, S Liang - Advances in mathematical and …, 2023 - books.google.com
With recent advancements in applications of artificial intelligence in medicine and biology,
predictive modeling has gradually become one of the primary directions in cancer research …

[PDF][PDF] Computational Modeling of Cancer Initiation and Locoregional Recurrence with Spatial Structure

AS DAHIRU - tus.repo.nii.ac.jp
Local and regional recurrence after surgical intervention is a significant problem in cancer
management. The multistage theory of carcinogenesis precisely places the presence of …