[HTML][HTML] What makes a multidisciplinary medication review and deprescribing intervention for older people work well in primary care? A realist review and synthesis

E Radcliffe, R Servin, N Cox, S Lim, QY Tan, C Howard… - BMC geriatrics, 2023 - Springer
Background A third of older people take five or more regular medications (polypharmacy).
Conducting medication reviews in primary care is key to identify and reduce/stop …

A systematic review of randomised-controlled trials on deprescribing outcomes in older adults with polypharmacy

H Omuya, C Nickel, P Wilson… - International Journal of …, 2023 - academic.oup.com
Background Mixed findings about deprescribing impact have emerged from varied study
designs, interventions, outcome measures and targeting sub-categories of medications or …

[HTML][HTML] Recent updates on risk and management plans associated with polypharmacy in older population

AM Alshanberi - Geriatrics, 2022 - mdpi.com
The concept of polypharmacy encompasses adverse drug reactions and non-adherence
factors in elderly individuals. It also leads to the increased use of healthcare services and …

[HTML][HTML] Consultation-based deprescribing service to optimize palliative care for terminal cancer patients

M Ko, S Kim, SY Suh, YS Cho, IW Kim, SH Yoo… - Journal of Clinical …, 2023 - mdpi.com
(1) Background: A pharmacist-led deprescribing service previously developed within the
Consultation-Based Palliative Care Team (CB-PCT) was implemented for terminal cancer …

[HTML][HTML] Prevalence and severity of potential drug–drug interactions in patients with multiple sclerosis with and without polypharmacy

P Bachmann, N Frahm, JL Debus, P Mashhadiakbar… - Pharmaceutics, 2022 - mdpi.com
Polypharmacy (PP) is a common problem in modern medicine, especially known to affect
patients with chronic diseases such as multiple sclerosis (MS). With an increasing number of …

Deprescribing considerations for older people in general practice

HW Quek, A Page, K Potter… - Australian Journal of …, 2023 - search.informit.org
Background Deprescribing is an integral part of patient care. The term'deprescribing'may be
new to some, but the concept is not. Deprescribing refers to the planned withdrawal of …

Self-reported reasons for reducing or stopping antidepressant medications in primary care: thematic analysis of the diamond longitudinal study

A Coe, J Gunn, S Fletcher, E Murray… - Primary Health Care …, 2023 - cambridge.org
Background: Current treatment guidelines advise that the deprescribing of antidepressants
should occur around 6 months post-remission of symptoms. However, this is not routinely …

[HTML][HTML] General practice patients' experiences and perceptions of the WiserAD structured web-based support tool for antidepressant deprescribing: protocol for a …

A Coe, J Gunn, C Kaylor-Hughes - JMIR Research Protocols, 2022 - researchprotocols.org
Background: Research suggests that the rapid increase in worldwide antidepressant use is
mainly due to a rise in long-term and potentially inappropriate use. It has been suggested …

[HTML][HTML] Evaluation of a multicomponent intervention consisting of education and feedback to reduce benzodiazepine prescriptions by general practitioners: The …

C Vicens, A Leiva, F Bejarano, E Sempere-Verdú… - PLoS …, 2022 - journals.plos.org
Background Current benzodiazepine (BZD) prescription guidelines recommend short-term
use to minimize the risk of dependence, cognitive impairment, and falls and fractures …

[HTML][HTML] Uptake of pharmacist recommendations by patients after discharge: Implementation study of a patient-centered medicines review service

BJ Basger, RJ Moles, TF Chen - BMC geriatrics, 2023 - Springer
Background Polypharmacy and potentially inappropriate medicine use is common in older
people, resulting in harm increased by lack of patient-centred care. Hospital clinical …