The ex vivo generation of platelets from human-induced pluripotent cells (hiPSCs) is
expected to compensate donor-dependent transfusion systems. However, manufacturing the …

Platelet products are used in treatments for thrombocytopenia caused by hematopoietic
diseases, chemotherapy, massive hemorrhages, extracorporeal circulation, and others …

Activation of coagulation and fibrinolysis is frequently encountered among cancer patients.
Such tumors are supposed to be associated with higher risk of invasion, metastases and …

The treatment goal for patients with immune thrombocytopaenia (ITP) is to raise platelet
counts to levels that minimize or stop bleeding. Thrombopoietin receptor agonists (TPO …

Objective Epithelial ovarian cancer (EOC) is the leading cause of death among
gynecological tumors and usually diagnosed at advanced stage. We aimed to identify the …

The 12-lipoxygenase pathway of arachidonic acid metabolism in platelets and other cells is
bifurcated into a reduction route yielding 12-hydroxyeicosatetraenoic acid (12-HETE) and an …

Quebec platelet disorder (QPD) is an inherited bleeding disorder associated with increased
urokinase plasminogen activator (uPA) in platelets but not in plasma, intraplatelet plasmin …

Dynamin 3 (DNM3) is a member of a family of motor proteins that participate in a number of
membrane rearrangements such as cytokinesis, budding of transport vesicles, phagocytosis …

Dengue virus (DV) infections cause mild dengue fever or severe life-threatening dengue
haemorrhagic fever (DHF)/dengue shock syndrome (DSS). DV-infected patients have high …

The aims of this study are to:(a) confirm the prognostic significance of the procoagulant
molecules D dimer, thrombin–antithrombin complex (TAT), and plasmin-α2–plasmin …