Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood
flow to the particular organ. IRI usually is associated with a robust inflammatory and …

Although there has been technical and pharmacological progress in kidney transplant
medicine, some patients may experience acute post-transplant complications. Among the …

Dexmedetomidine is a highly selective alpha-2 agonist that provides anxiolysis and
cooperative sedation without respiratory depression. It decreases central nervous system …

Background Renal ischemia–reperfusion (I/R) may cause acute lung injury (ALI). The
mortality of combined acute kidney injury and ALI is extremely high. Dexmedetomidine, an …

Dexmedetomidine (DEX), a highly specific α2‑adrenergic agonist, which exhibits
anaesthetic‑sparing, analgesia and sympatholytic properties. DEX modulates gene …

Background Intestinal ischemia-reperfusion (I/R) injury is a devastating complication in the
perioperative period. Dexmedetomidine is commonly applied in the perioperative period …

Background Transient global cerebral ischemia/reperfusion (I/R) is a major perioperative
complication, and diabetes increases the response of oxidative stress and inflammation …

Dexmedetomidine is an α2-adrenergic receptor agonist that exhibits a protective effect on
ischemia-reperfusion injury of the heart, kidney, and other organs. In the present study, we …

Abstract Background Dexmedetomidine (Dex) can improve neuronal viability and protect the
spinal cord from ischemia–reperfusion (I/R) injury, but the underlying mechanisms are not …

AIM: To investigate the protective effects of dexmedetomidine against hepatic
ischemia/reperfusion (IR) injury and hepatic IR induced remote organ injury. METHODS …