Advances in glycoside and oligosaccharide synthesis

CJ Crawford, PH Seeberger - Chemical Society Reviews, 2023 - pubs.rsc.org
The structural complexity of glycans poses a serious challenge in the chemical synthesis of
glycosides, oligosaccharides and glycoconjugates. Glycan complexity, determined by …

Realizing the continuous Chemoenzymatic synthesis of Anilines using an immobilized nitroreductase

SC Cosgrove, GJ Miller, A Bornadel… - ACS Sustainable …, 2023 - ACS Publications
The use of biocatalysis for classically synthetic transformations has seen an increase in
recent years, driven by the sustainability credentials bio-based approaches can offer the …

Tandem One-Pot Biocatalytic Oxidation and Wittig Reaction in Water

AJC Wahart, LND Beardmore, RA Field… - Organic …, 2024 - ACS Publications
We explore biocatalytic aldehyde generation under aqueous conditions, concomitantly
delivering access to a one-pot Wittig reaction using stabilized phosphoranes and granting …

A bifunctional Pasteurella multocida β1–3-galactosyl/N-acetylgalactosaminyltransferase (PmNatB) for the highly efficient chemoenzymatic synthesis of disaccharides

X Yang, B Mishra, H Yu, Y Wei, X Chen - Organic & Biomolecular …, 2024 - pubs.rsc.org
Glycosyltransferases are nature's key biocatalysts for the formation of glycosidic bonds.
Discovery and characterization of new synthetically useful glycosyltransferases are critical …

Harnessing a biocatalyst to bioremediate the purification of alkylglycosides

AJC Wahart, JP Dolan, SD Anderson… - …, 2024 - Wiley Online Library
As the world moves towards net‐zero carbon emissions, the development of sustainable
chemical manufacturing processes is essential. Within manufacturing, purification by …

The Conversion of UDP‐Glc to UDP‐Man: In Silico and Biochemical Exploration To Improve the Catalytic Efficiency of CDP‐Tyvelose C2‐Epimerases

U Vogel, M Da Costa, C Alvarez Quispe… - …, 2023 - Wiley Online Library
A promiscuous CDP‐tyvelose 2‐epimerase (TyvE) from Thermodesulfatator atlanticus
(TaTyvE) belonging to the nucleotide sugar active short‐chain dehydrogenase/reductase …

Fluorinated nucleosides, nucleotides and sugar nucleotides

JP Dolan, CMM Benckendorff, RA Field… - Future Medicinal …, 2023 - Taylor & Francis
In this editorial we highlight the inclusion of fluorine within the building blocks for
biomolecule assembly, namely, within nucleoside analogs, as precursors to nucleotides and …

[引用][C] Synthesis of Glycosides

CJ Crawford, PH Seeberger - 2023 - Elsevier

[引用][C] Flow Biocatalysis for Chiral Molecules Synthesis