Abstract Alcohol Use Disorder (AUD) is a multifaceted relapsing disorder that is commonly
comorbid with psychiatric disorders, including anxiety. Alcohol exposure produces a …

Individual differences in drug response have always existed in clinical treatment. Many non‐
genetic factors show non‐negligible impacts on personalized medicine. Emerging studies …

Tobacco, alcohol, and marijuana consumption is an important public health problem
because of their high use worldwide and their association with the risk of mortality and many …

Excessive alcohol consumption has detrimental effects on the entire organism, especially on
the liver. The toxicity is partly dependent on age, as older individuals metabolize alcohol …

Characterising associations between the methylome, proteome and phenome may provide
insight into biological pathways governing brain health. Here, we report an integrated DNA …

Alcohol use disorder (AUD) is a pervasive and devastating mental illness with high
comorbidity rates with other mental disorders. Understanding the genetic architecture of this …

Chronic heavy alcohol consumption is associated with increased mortality and morbidity
and often leads to premature aging; however, the mechanisms of alcohol-associated cellular …

Background Smoking and alcohol consumption may compromise health by way of
epigenetic modifications. Epigenetic signatures of alcohol and tobacco consumption could …

Background: Many epigenetic loci have been associated with plasma triglyceride (TG)
levels, but epigenetic connections between those loci and dietary exposures are largely …

The epigenome likely interacts with traditional and genetic risk factors to influence blood
pressure. We evaluated whether 13 previously reported DNA methylation sites (CpGs) are …