Low-Dose Colchicine for Secondary Prevention of Coronary Artery Disease: JACC Review Topic of the Week

K Nelson, V Fuster, PM Ridker - Journal of the American College of …, 2023 - jacc.org
Among statin-treated patients, inflammation assessed by means of high-sensitivity C-
reactive protein (hsCRP) is a more powerful determinant of cardiovascular death and all …

Established and emerging lipid-lowering drugs for primary and secondary cardiovascular prevention

DT Michaeli, JC Michaeli, S Albers, T Boch… - American Journal of …, 2023 - Springer
Despite treatment with statins, patients with elevated low-density lipoprotein cholesterol
(LDL-C) and triglycerides remain at increased risk for adverse cardiovascular events …

Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials

PM Ridker, DL Bhatt, AD Pradhan, RJ Glynn… - The Lancet, 2023 - thelancet.com
Background Inflammation and hyperlipidaemia jointly contribute to atherothrombotic
disease. However, when people are treated with intensive statin therapy, the relative …

Overview and new insights into the metabolic syndrome: risk factors and emerging variables in the development of type 2 diabetes and cerebrocardiovascular disease

MR Hayden - Medicina, 2023 - mdpi.com
Metabolic syndrome (MetS) is considered a metabolic disorder that has been steadily
increasing globally and seems to parallel the increasing prevalence of obesity. It consists of …

Triglyceride and triglyceride-rich lipoproteins in atherosclerosis

BH Zhang, F Yin, YN Qiao, SD Guo - Frontiers in Molecular …, 2022 - frontiersin.org
Cardiovascular disease (CVD) is still the leading cause of death globally, and
atherosclerosis is the main pathological basis of CVDs. Low-density lipoprotein cholesterol …

Nanomaterials responsive to endogenous biomarkers for cardiovascular disease theranostics

C Wei, Z Jiang, C Li, P Li, Q Fu - Advanced Functional Materials, 2023 - Wiley Online Library
Cardiovascular disease (CVD) is the number one cause of death worldwide, which propels
the development of advanced technologies for CVD diagnosis and treatment. Biomarker …

CpG-Conjugated Silver Nanoparticles as a Multifunctional Nanomedicine to Promote Macrophage Efferocytosis and Repolarization for Atherosclerosis Therapy

C Tang, H Wang, L Guo, C Zou, J Hu… - … Applied Materials & …, 2023 - ACS Publications
Atherosclerosis (AS) is a major contributor to cardiovascular diseases, necessitating the
development of novel therapeutic strategies to alleviate plaque burden. Macrophage …

Contribution of intestinal triglyceride-rich lipoproteins to residual atherosclerotic cardiovascular disease risk in individuals with type 2 diabetes on statin therapy

MR Taskinen, N Matikainen, E Björnson, S Söderlund… - Diabetologia, 2023 - Springer
Aims/hypothesis This study explored the hypothesis that significant abnormalities in the
metabolism of intestinally derived lipoproteins are present in individuals with type 2 diabetes …

Lipoproteins, cholesterol, and atherosclerotic cardiovascular disease in East Asians and Europeans

T Doi, A Langsted, BG Nordestgaard - Journal of Atherosclerosis and …, 2023 - jstage.jst.go.jp
One fifth of the world population live in East Asia comprising Japan, Korea, and China where
ischemic heart disease, a major component of atherosclerotic cardiovascular disease …

[HTML][HTML] APOC3 inhibition with volanesorsen reduces hepatic steatosis in patients with severe hypertriglyceridemia

TA Prohaska, VJ Alexander… - Journal of Clinical …, 2023 - Elsevier
ApoC-III inhibits lipoprotein lipase and hepatic uptake of triglyceride-rich lipoproteins. It is
unknown whether targeting apoC-III affects hepatic steatosis in patients with …