International Union of Basic and Clinical Pharmacology. CV. Somatostatin receptors: structure, function, ligands, and new nomenclature

T Günther, G Tulipano, P Dournaud, C Bousquet… - Pharmacological …, 2018 - ASPET
Somatostatin, also known as somatotropin-release inhibitory factor, is a cyclopeptide that
exerts potent inhibitory actions on hormone secretion and neuronal excitability. Its …

Colorectal cancer invasion and atrophy of the enteric nervous system: potential feedback and impact on cancer progression

J Godlewski, Z Kmiec - International journal of molecular sciences, 2020 - mdpi.com
Colorectal cancer (CRC) invasion within the large intestine wall results in the replacement of
normal tissue architecture by tumour mass. Cancer cells digest the extracellular matrix …

The neuropeptide system and colorectal cancer liver metastases: mechanisms and management

A Kasprzak, A Adamek - International journal of molecular sciences, 2020 - mdpi.com
Colorectal cancer (CRC), classified as the third most prevalent cancer worldwide, remains to
be a clinical and research challenge. It is estimated that~ 50% of CRC patients die from …

Somatostatin and its receptor system in colorectal cancer

A Kasprzak - Biomedicines, 2021 - mdpi.com
Somatostatin (SST)/somatotropin release-inhibiting factor (SRIF) is a well-known
neuropeptide, widely distributed in the central and peripheral nervous systems, that …

The prognostic and therapeutic role of hormones in colorectal cancer: a review

S Nikolaou, S Qiu, F Fiorentino, S Rasheed… - Molecular biology …, 2019 - Springer
Colorectal cancer (CRC) is one of the commonest cancers in Western society with a poor
prognosis in patients with advanced disease. Targeted therapy is of increasing interest and …

Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and …

JK Hennigs, J Mueller, M Adam, JM Spin, E Riedel… - PLoS …, 2014 - journals.plos.org
Somatostatin receptor subtype 2 (SSTR2) is the most frequently expressed SSTR subtype in
normal human tissues. SSTR2 expression is differentially regulated in various tumor types …

藤龙补中汤对大肠癌RKO 细胞转移相关基因表达影响

胡兵, 安红梅, 郑佳露, 闫霞, 黄晓伟, 李淼 - 中国中西医结合消化杂志, 2018 - whuhzzs.com
[目的] 观察藤龙补中汤对人大肠癌RKO 细胞转移相关基因表达影响.[方法] 藤龙补中汤处理RKO
细胞, TRIzol 试剂提取RNA, 试剂盒纯化RNA, 肿瘤转移PCR 芯片(Tumor metastasis PCR …

Pattern of somatostatin receptors expression in normal and bladder cancer tissue samples

M Karavitakis, P Msaouel, V Michalopoulos… - Anticancer …, 2014 - ar.iiarjournals.org
Background/Aim: Known risks factors for bladder cancer progression and recurrence are
limited regarding their prognostic ability. Therefore identification of molecular determinants …

Time-of-Flight PET/CT Imaging of Ga-68-Dotatate: Normal Pattern, SUV Quantification, and Differences from Non-Time-of-Flight Imaging

MC Miller, AT Bansal, D Wingard… - World Journal of …, 2024 - thieme-connect.com
Purpose The biodistribution of gallium-68-dotatate (Ga-68-dotatate) and standardized
uptake values (SUVs) using non-time-of-flight (TOF) positron emission …

生长抑素受体2 在结直肠癌中的表达

程元光, 吴佩 - 中国临床药理学与治疗学, 2013 - manu41.magtech.com.cn
目的: 检测生长抑素Ⅱ 型受体(SSR2) mRNA 在结直肠癌组织中的表达并研究其在结直肠癌发生
, 发展中的作用. 方法: 采用逆转录聚合酶链反应(Reverse transcription-PCR, RT-PCR) …