Human schistosomiasis

DG Colley, AL Bustinduy, WE Secor, CH King - The Lancet, 2014 - thelancet.com
Human schistosomiasis—or bilharzia—is a parasitic disease caused by trematode flukes of
the genus Schistosoma. By conservative estimates, at least 230 million people worldwide …

Time to set the agenda for schistosomiasis elimination

D Rollinson, S Knopp, S Levitz, JR Stothard… - Acta tropica, 2013 - Elsevier
It is time to raise global awareness to the possibility of schistosomiasis elimination and to
support endemic countries in their quest to determine the most appropriate approaches to …

Human schistosomiasis

B Gryseels, K Polman, J Clerinx, L Kestens - The lancet, 2006 - thelancet.com
Schistosomiasis or bilharzia is a tropical disease caused by worms of the genus
Schistosoma. The transmission cycle requires contamination of surface water by excreta …

Susceptibility or resistance of praziquantel in human schistosomiasis: a review

W Wang, L Wang, YS Liang - Parasitology research, 2012 - Springer
Since praziquantel was developed in 1970s, it has replaced other antischistosomal drugs to
become the only drug of choice for treatment of human schistosomiases, due to high …

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

MJ Doenhoff, D Cioli, J Utzinger - Current opinion in infectious …, 2008 - journals.lww.com
Use of PZQ will increase in the foreseeable future, whether given alone or coadministered
with other anthelminthics in integrated control programmes. PZQ resistance remains a threat …

Global epidemiology, ecology and control of soil-transmitted helminth infections

S Brooker, ACA Clements, DAP Bundy - Advances in parasitology, 2006 - Elsevier
Soil-transmitted helminth (STH) infections are among the most prevalent of chronic human
infections worldwide. Based on the demonstrable impact on child development, there is a …

Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?

R Bergquist, J Utzinger, J Keiser - Infectious diseases of poverty, 2017 - Springer
The current approach of morbidity control of schistosomiasis, a helminth disease of poverty
with considerable public health and socioeconomic impact, is based on preventive …

Schistosomiasis and neglected tropical diseases: towards integrated and sustainable control and a word of caution

J Utzinger, G Raso, S Brooker, D De Savigny… - Parasitology, 2009 - cambridge.org
In May 2001, the World Health Assembly (WHA) passed a resolution which urged member
states to attain, by 2010, a minimum target of regularly administering anthelminthic drugs to …

Helminth infections: soil-transmitted helminth infections and schistosomiasis

PJ Hotez, DAP Bundy, K Beegle, S Brooker, L Drake… - 2006 - repository.kln.ac.lk
Peter J. Hotez, Donald AP Bundy, Kathleen Beegle, Simon Brooker, Lesley Drake, Nilanthi
de Silva, Antonio Montresor, Dirk Engels, Matthew Jukes, Lester Chitsulo, Jeffrey Chow …

Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni

SD Melman, ML Steinauer… - PLoS neglected …, 2009 - journals.plos.org
Background The near exclusive use of praziquantel (PZQ) for treatment of human
schistosomiasis has raised concerns about the possible emergence of drug-resistant …