Elevated levels of cyclin A1 expression have been implicated in acute myeloid leukemia and
in male germ cell tumors. However, a role of cyclin A1 in tumorigenesis of prostate cancer …

Despite recent advances in the treatment of advanced prostate cancer (PCa), metastatic
castrate-resistant PCa remains incurable at this time. The androgen receptor (AR) plays a …

Prolonged bicalutamide treatment induced pathology regression although relapses with a
more aggressive form of prostate cancer have been observed. This failure could be due to …

It has been recently shown that cannabinoids may regulate the growth of many cell types. In
the present work we examined the effect of the anandamide analogue (R)-methanandamide …

Prostate and breast cancer are the two cancers with the highest incidence in men and
women, respectively. Here, we focus on the known biology of acquired resistance to …

Degarelix (FE 200486) is a member of a new class of water-soluble (> 50 mg/ml)
gonadotropin-releasing hormone (GnRH) antagonists in clinical development for prostate …

Considering the increasing importance of cyclopropyl-containing peptide-derived
compounds in the pharmaceutical industry, herein, we report the crystal engineering of a …

Accumulating epidemiological data suggest that Asian men have lower incidences of
prostate cancer and benign prostate hyperplasia (BPH) compared with American and …

Androgens are important for male sexual development, which depend on the cognate
receptor, the androgen receptor. The transcriptional activity of the androgen receptor, like …

Evidence suggests that 17 β-estradiol (E2) contributes to the risk of prostate cancer (PCa),
whereas the phytochemicals genistein from soy and 3, 3´-diindolylmethane (DIM), derived …