Role of NRF2 in ovarian cancer

G Tossetta, S Fantone, E Montanari, D Marzioni… - Antioxidants, 2022 - mdpi.com
Among gynaecologic malignancies, ovarian cancer is one of the most dangerous, with a
high fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …

Natural and synthetic compounds in Ovarian Cancer: A focus on NRF2/KEAP1 pathway

G Tossetta, D Marzioni - Pharmacological Research, 2022 - Elsevier
Among gynecologic malignancies, ovarian cancer is one of the most dangerous, with a high
fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …

Targeting the NRF2/KEAP1 pathway in cervical and endometrial cancers

G Tossetta, D Marzioni - European Journal of Pharmacology, 2023 - Elsevier
Cervical and endometrial cancers are among the most dangerous gynaecological
malignancies, with high fatality and recurrence rates due to frequent diagnosis at an …

Antioxidants in brain tumors: current therapeutic significance and future prospects

X Qi, SK Jha, NK Jha, S Dewanjee, A Dey, R Deka… - Molecular Cancer, 2022 - Springer
Brain cancer is regarded among the deadliest forms of cancer worldwide. The distinct tumor
microenvironment and inherent characteristics of brain tumor cells virtually render them …

Molecular targets of natural compounds with anti-cancer properties

M Kubczak, A Szustka, M Rogalińska - International Journal of Molecular …, 2021 - mdpi.com
Cancer is the second leading cause of death in humans. Despite rapid developments in
diagnostic methods and therapies, metastasis and resistance to administrated drugs are the …

Phytochemicals in cancer treatment and cancer prevention—review on epidemiological data and clinical trials

A Rudzińska, P Juchaniuk, J Oberda, J Wiśniewska… - Nutrients, 2023 - mdpi.com
Phytochemicals are a non-nutritive substances that are present in plants and contribute
significantly to their flavor and color. These biologically active compounds are classified into …

Enzymatic metabolism of flavonoids by gut microbiota and its impact on gastrointestinal cancer

RK Al-Ishaq, A Liskova, P Kubatka, D Büsselberg - Cancers, 2021 - mdpi.com
Simple Summary Flavonoid's consumption is reported to impact GI cancer progression
positively. As 90% of flavonoids consumed, undergo metabolism and conversion by the …

Role of natural and synthetic compounds in modulating NRF2/KEAP1 signaling pathway in prostate cancer

G Tossetta, S Fantone, D Marzioni, R Mazzucchelli - Cancers, 2023 - mdpi.com
Simple Summary Several studies showed that oxidative stress is involved in cancer
occurrence, development, progression chemoresistance and radio resistance. The nuclear …

[HTML][HTML] Icariin as an emerging candidate drug for anticancer treatment: Current status and perspective

Y Liu, H Yang, J Xiong, J Zhao, M Guo, J Chen… - Biomedicine & …, 2023 - Elsevier
Icariin (ICA) is a kind of natural flavonoid compound monomer, which is derived from the
extract of dried stems and leaves of Epimedium. Modern pharmacological studies have …

Flavonoids nanostructures promising therapeutic efficiencies in colorectal cancer

S Hassani, H Maghsoudi, F Fattahi… - International Journal of …, 2023 - Elsevier
Colorectal cancer is among the frequently diagnosed cancers with high mortality rates
around the world. Polyphenolic compounds such as flavonoids are secondary plant …